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ACIU

AC Immune SA

Price Chart
Latest Quote

$2.25

-0.15 (-6.25%)
Current Price
Previous Close $2.40
Open $2.39
Day High $2.46
Day Low $2.21
Volume 327,527
Fetched: 2026-06-06T01:17:26
Stock Information
Note: Financial values converted from CHF to USD
Shares Outstanding 101.77M
Total Debt $5.41M
Cash Equivalents $93.94M
Revenue $4.65M
Net Income $-83.17M
Sector Healthcare
Industry Biotechnology
Market Cap $228.99M
EPS (TTM) $-0.84
Exchange NGM
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📊 Comprehensive Analysis
Company Data
Enterprise Value$151.52M
Sales$4.65M
Income$-83.17M
Book/sh$0.41
Cash/sh$0.73
Employees90
Financial Ratios
Quick Ratio0.83
Current Ratio0.87
Debt/Eq13.65
Returns & Margins
ROA-23.06%
ROE-104.83%
Operating Margin-1321.54%
Ownership
Insider Ownership37.87%
Institutional Ownership24.83%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E15.35
P/S61.86
P/B5.54
Analyst Data
Recommendationnone
Target Price$8.83
Technical Indicators
SMA20$2.71
SMA50$2.87
SMA200$2.97
RSI23.00
ATR0.1631
Shares Float38.71M
Short Float6.61%
Short Ratio11.67
Volatility1.56
Rel Volume1.14
Performance History
Week-15.41%
Month-24.24%
Quarter-19.35%
6 Months-21.05%
YTD-33.04%
Year+34.73%
3 Years+3.21%
5 Years-63.05%
10 Years-85.63%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-05 $2.25 327,527
2026-06-04 $2.40 218,400
2026-06-03 $2.39 252,100
2026-06-02 $2.42 546,000
2026-06-01 $2.46 449,700
2026-05-29 $2.66 293,100
2026-05-28 $2.75 196,400
2026-05-27 $2.93 173,700
2026-05-26 $2.93 310,900
2026-05-22 $2.83 78,100
2026-05-21 $2.85 146,700
2026-05-20 $2.89 178,200
2026-05-19 $2.82 272,400
2026-05-18 $2.77 224,800
2026-05-15 $2.79 357,200
2026-05-14 $2.80 368,900
2026-05-13 $2.84 251,200
2026-05-12 $2.77 446,400
2026-05-11 $2.83 310,200
2026-05-08 $2.86 342,800
2026-05-07 $2.92 200,900
2026-05-06 $2.97 345,700
About AC Immune SA

AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti-Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589 and ACI-15916, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative diseases. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $4,576,369 $34,977,908 $18,957,414 $5,040,026
Operating Revenue $4,576,369 $34,977,908 $18,957,414 $5,040,026
Expenses
Interest Expense $244,637 $170,349 $225,424 $454,691
Total Expenses $92,777,463 $102,064,687 $87,640,095 $95,782,266
Other Income Expense $-4,172,911 $-2,046,750 $-1,878,963 $503,362
Net Non Operating Interest Income Expense $2,144,092 $3,923,151 $1,111,752 $-366,314
Interest Expense Non Operating $244,637 $170,349 $225,424 $454,691
Operating Expense $92,777,463 $102,064,687 $87,640,095 $95,782,266
Other Operating Expenses $3,497,919 $5,802,114 $2,781,941 $6,229,908
General And Administrative Expense $14,924,112 $14,644,894 $13,545,950 $12,272,815
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Net Interest Income $2,144,092 $3,923,151 $1,111,752 $-366,314
Interest Income $2,388,729 $4,093,500 $1,337,176 $88,377
Normalized Income $-86,057,002 $-63,341,445 $-67,743,449 $-91,059,768
Net Income From Continuing And Discontinued Operation $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Total Operating Income As Reported $-88,783,867 $-67,086,779 $-68,682,681 $-90,742,240
Net Income Common Stockholders $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Net Income $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Net Income Including Noncontrolling Interests $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Net Income Continuous Operations $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Pretax Income $-90,229,912 $-65,210,378 $-69,449,892 $-90,605,193
Special Income Charges $-582,773 $0 $0 -
Interest Income Non Operating $2,388,729 $4,093,500 $1,337,176 $88,377
Operating Income $-88,201,094 $-67,086,779 $-68,682,681 $-90,742,240
Depreciation Amortization Depletion Income Statement $2,071,086 $1,476,785 $1,371,758 -
Depreciation And Amortization In Income Statement $2,071,086 $1,476,785 $1,371,758 -
Depreciation Income Statement $2,071,086 $1,476,785 $1,371,758 -
Per Share
Diluted EPS $-0.90 $-0.65 $-0.82 $-1.09
Basic EPS $-0.90 $-0.65 $-0.82 $-1.09
Other
Tax Effect Of Unusual Items $0 $-173,974 $-159,712 $65,437
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-82,606,473 $-60,224,147 $-64,508,489 $-87,632,410
Total Unusual Items $-4,172,911 $-2,046,750 $-1,878,963 $503,362
Total Unusual Items Excluding Goodwill $-4,172,911 $-2,046,750 $-1,878,963 $503,362
Reconciled Depreciation $3,205,892 $2,769,132 $2,837,016 $3,021,454
EBITDA (Bullshit earnings) $-86,779,384 $-62,270,897 $-66,387,452 $-87,129,048
EBIT $-89,985,276 $-65,040,029 $-69,224,468 $-90,150,502
Diluted Average Shares $129,044,779 $127,871,021 $108,478,541 $107,018,145
Basic Average Shares $129,044,779 $127,871,021 $108,478,541 $107,018,145
Diluted NI Availto Com Stockholders $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Tax Provision $0 $3,842 $12,808 $16,651
Restructuring And Mergern Acquisition $582,773 $0 $0 -
Gain On Sale Of Security $-3,590,138 $-2,046,750 $-1,878,963 $503,362
Research And Development $72,284,346 $80,140,895 $69,940,446 $77,279,543
Selling General And Administration $14,924,112 $14,644,894 $13,545,950 $12,272,815
Salaries And Wages $14,924,112 $14,644,894 $13,545,950 $12,272,815
Fetched: 2026-05-30
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $-7,085,495 $79,223,828 $141,180,924 $151,873,208
Total Assets $197,567,735 $295,757,942 $234,151,791 $238,153,072
Total Non Current Assets $73,684,282 $75,464,622 $73,853,350 $74,087,741
Other Non Current Assets $1,281 - - -
Investmentin Financial Assets $747,999 $531,540 $462,376 $462,376
Goodwill And Other Intangible Assets $64,573,811 $64,573,811 $64,573,811 $64,573,811
Other Intangible Assets $64,573,811 $64,573,811 $64,573,811 $64,573,811
Current Assets $123,883,453 $220,293,321 $160,298,440 $164,065,331
Prepaid Assets $5,087,416 $5,510,087 $8,244,637 $6,030,100
Receivables $1,713,737 $2,821,646 $20,067,885 $1,024,656
Other Receivables $563,561 $1,592,059 $372,719 $681,396
Taxes Receivable $1,150,176 $1,229,587 $739,033 $343,260
Cash Cash Equivalents And Short Term Investments $117,082,300 $211,961,588 $131,985,919 $157,010,576
Cash And Cash Equivalents $34,319,567 $46,461,738 $100,536,669 $40,455,974
Accounts Receivable - $0 $18,956,133 $0
Debt
Total Debt $5,816,203 $6,951,009 $4,479,027 $3,587,576
Long Term Debt And Capital Lease Obligation $4,724,944 $5,636,888 $3,618,316 $2,885,687
Current Debt And Capital Lease Obligation $1,091,258 $1,314,121 $860,711 $701,889
Liabilities
Total Liabilities Net Minority Interest $140,079,419 $151,960,304 $28,397,056 $21,706,053
Total Non Current Liabilities Net Minority Interest $18,794,750 $22,804,997 $11,008,646 $7,000,961
Non Current Deferred Liabilities $2,995,838 $5,840,538 $0 -
Current Liabilities $121,284,669 $129,155,307 $17,388,410 $14,705,092
Current Deferred Liabilities $107,212,302 $108,941,409 $176,753 $751,841
Payables And Accrued Expenses $12,981,109 $18,899,777 $16,350,946 $13,251,362
Payables $2,648,735 $3,404,419 $2,150,496 $1,189,882
Accounts Payable $2,648,735 $3,404,419 $2,150,496 $1,189,882
Equity
Common Stock Equity $57,488,316 $143,797,639 $205,754,735 $216,447,019
Total Equity Gross Minority Interest $57,488,316 $143,797,639 $205,754,735 $216,447,019
Stockholders Equity $57,488,316 $143,797,639 $205,754,735 $216,447,019
Gains Losses Not Affecting Retained Earnings $8,966 $-6,404 $-65,322 $12,808
Retained Earnings $-562,306,789 $-471,647,802 $-404,991,378 $-338,155,639
Other
Treasury Shares Number $13,960,645 $13,960,645 $6,716,565 $7,959,041
Ordinary Shares Number $130,313,464 $128,607,599 $127,054,544 $107,102,618
Share Issued $144,274,109 $142,568,244 $133,771,109 $115,061,659
Tangible Book Value $-7,085,495 $79,223,828 $141,180,924 $151,873,208
Invested Capital $57,488,316 $143,797,639 $205,754,735 $216,447,019
Working Capital $2,598,783 $91,138,014 $142,910,031 $149,360,239
Capital Lease Obligations $5,816,203 $6,951,009 $4,479,027 $3,587,576
Total Capitalization $57,488,316 $143,797,639 $205,754,735 $216,447,019
Foreign Currency Translation Adjustments $8,966 $-6,404 $-65,322 $12,808
Treasury Stock $279,219 $279,219 $134,486 $158,822
Additional Paid In Capital $617,179,671 $612,879,959 $608,270,289 $552,447,039
Capital Stock $2,885,687 $2,851,105 $2,675,633 $2,301,633
Common Stock $2,885,687 $2,851,105 $2,675,633 $2,301,633
Employee Benefits $11,073,968 $11,327,570 $7,390,330 $4,115,274
Non Current Deferred Revenue $2,995,838 $5,840,538 $0 -
Long Term Capital Lease Obligation $4,724,944 $5,636,888 $3,618,316 $2,885,687
Current Deferred Revenue $107,212,302 $108,941,409 $176,753 $751,841
Current Capital Lease Obligation $1,091,258 $1,314,121 $860,711 $701,889
Current Accrued Expenses $10,332,373 $15,495,358 $14,200,449 $12,061,480
Investments And Advances $747,999 $531,540 $462,376 $462,376
Net PPE $8,361,192 $10,359,271 $8,817,164 $9,051,554
Accumulated Depreciation $-17,567,724 $-15,969,261 $-14,083,895 $-11,966,699
Gross PPE $25,928,916 $26,328,532 $22,901,058 $21,018,253
Leases $2,420,749 $2,386,167 $2,128,723 $2,100,544
Other Properties $14,005,765 $13,494,717 $13,106,629 $12,507,205
Machinery Furniture Equipment $3,778,418 $3,633,686 $3,252,001 $2,938,201
Buildings And Improvements $5,723,984 $6,813,961 $4,413,705 $3,468,460
Properties $0 $0 $0 $0
Other Short Term Investments $82,762,733 $165,499,850 $31,449,249 $116,554,602
Construction In Progress - $0 $0 $3,842
Fetched: 2026-05-30
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-89,864,879 $83,593,985 $-78,397,699 $-95,814,287
Operating Activities
Operating Cash Flow $-88,712,141 $84,331,737 $-77,371,762 $-94,227,351
Cash Flow From Continuing Operating Activities $-88,712,141 $84,331,737 $-77,371,762 $-94,227,351
Operating Gains Losses $-2,005,764 $-12,808 $1,137,368 $692,924
Investing Activities
Capital Expenditure $-1,152,738 $-737,752 $-1,025,937 $-1,586,936
Investing Cash Flow $81,385,852 $-134,857,517 $84,079,416 $30,436,121
Cash Flow From Continuing Investing Activities $81,385,852 $-134,857,517 $84,079,416 $30,436,121
Net Other Investing Changes $-217,739 $-69,164 - $2,562
Financing Activities
Issuance Of Capital Stock $7,685 $142,171 $56,097,346 $8,966
Financing Cash Flow $-1,306,436 $-1,434,518 $55,395,456 $-1,723,983
Cash Flow From Continuing Financing Activities $-1,306,436 $-1,434,518 $55,395,456 $-1,723,983
Net Common Stock Issuance $7,685 $142,171 $56,097,346 $-1,281
Common Stock Issuance $7,685 $142,171 $56,097,346 $8,966
Net Other Financing Charges - $-701,889 - $-993,916
Repurchase Of Capital Stock - - - $-10,247
Other
Repayment Of Debt $-1,314,121 $-874,800 $-701,889 $-728,786
End Cash Position $34,319,567 $46,461,738 $100,536,669 $40,455,974
Beginning Cash Position $46,461,738 $100,536,669 $40,455,974 $105,303,881
Effect Of Exchange Rate Changes $-3,509,446 $-2,114,633 $-2,022,414 $667,307
Changes In Cash $-8,632,725 $-51,960,298 $62,103,110 $-65,515,214
Net Issuance Payments Of Debt $-1,314,121 $-874,800 $-701,889 $-728,786
Net Long Term Debt Issuance $-1,314,121 $-874,800 $-701,889 $-728,786
Long Term Debt Payments $-1,314,121 $-874,800 $-701,889 $-728,786
Net Investment Purchase And Sale $82,737,117 $-134,050,600 $85,105,352 $32,020,495
Net PPE Purchase And Sale $-1,133,526 $-737,752 $-1,025,937 $-1,586,936
Sale Of PPE $19,212 $0 $0 $0
Purchase Of PPE $-1,152,738 $-737,752 $-1,025,937 $-1,586,936
Interest Received Cfo $2,429,715 $2,001,921 $762,088 $88,377
Interest Paid Cfo $-242,075 $-165,226 $-225,424 $-612,232
Change In Working Capital $-8,677,554 $137,706,060 $-19,417,228 $-10,799,873
Change In Other Working Capital $-4,573,808 $114,605,194 $-575,088 $-166,507
Change In Payables And Accrued Expense $-5,703,491 $3,009,927 $2,442,523 $-9,205,252
Change In Accrued Expense $-4,945,245 $1,758,566 $1,456,292 $-7,830,932
Change In Payable $-758,245 $1,251,361 $986,231 $-1,374,320
Change In Prepaid Assets $422,671 $2,734,550 $-2,238,873 $-2,200,448
Change In Receivables $1,177,073 $17,356,389 $-19,045,790 $772,334
Changes In Account Receivables $0 $18,956,133 $-18,956,133 $0
Other Non Cash Items $1,177,073 $240,794 $1,406,340 $-261,287
Stock Based Compensation $5,630,484 $7,006,084 $5,590,778 $4,265,130
Depreciation Amortization Depletion $3,205,892 $2,769,132 $2,837,016 $3,021,454
Depreciation And Amortization $3,205,892 $2,769,132 $2,837,016 $3,021,454
Depreciation $3,205,892 $2,769,132 $2,837,016 $3,021,454
Pension And Employee Benefit Expense $-1,986,552 $-12,808 $1,137,368 $692,924
Gain Loss On Sale Of PPE $-19,212 $0 $0 $0
Net Income From Continuing Operations $-90,229,912 $-65,214,221 $-69,462,700 $-90,621,843
Issuance Of Debt - - $0 $0
Long Term Debt Issuance - - $0 $0
Proceeds From Stock Option Exercised - - - $8,966
Common Stock Payments - - - $-10,247
Net Short Term Debt Issuance - - - $0
Short Term Debt Payments - - - $0
Fetched: 2026-05-30