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APRE

Aprea Therapeutics, Inc.

Price Chart
Latest Quote

$0.78

+0.01 (+1.75%)
Current Price
Previous Close $0.76
Open $0.75
Day High $0.81
Day Low $0.75
Volume 49,334
Fetched: 2026-06-04T20:59:30
Stock Information
Shares Outstanding 12.38M
Cash Equivalents $46.47M
Revenue $123K
Net Income $-11.95M
Sector Healthcare
Industry Biotechnology
Market Cap $9.18M
EPS (TTM) $-1.49
Exchange NCM
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📊 Comprehensive Analysis
Company Data
Enterprise Value$-36.56M
Sales$123K
Income$-11.95M
Book/sh$3.47
Cash/sh$3.75
Employees8
Financial Ratios
Quick Ratio8.77
Current Ratio8.92
Returns & Margins
ROA-23.18%
ROE-40.40%
Operating Margin-10202.01%
Ownership
Insider Ownership11.56%
Institutional Ownership18.13%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E-0.94
P/S74.46
P/B0.21
Analyst Data
Recommendationnone
Target Price$4.30
Technical Indicators
SMA20$0.87
SMA50$0.85
SMA200$1.05
RSI33.03
ATR0.0801
Shares Float8.57M
Short Float1.27%
Short Ratio0.58
Rel Volume0.57
Performance History
Week-17.02%
Month-11.15%
Quarter-17.67%
6 Months-28.06%
YTD-13.13%
Year-61.80%
3 Years-80.75%
5 Years-99.12%
10 Years-99.82%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-05 $0.74 106,700
2026-06-04 $0.77 51,900
2026-06-03 $0.76 124,900
2026-06-02 $0.76 127,300
2026-06-01 $0.82 230,600
2026-05-29 $0.89 123,800
2026-05-28 $0.93 109,000
2026-05-27 $0.92 91,900
2026-05-26 $0.91 110,500
2026-05-22 $0.95 189,900
2026-05-21 $0.93 194,100
2026-05-20 $0.90 261,500
2026-05-19 $0.80 146,700
2026-05-18 $0.85 160,600
2026-05-15 $0.93 116,200
2026-05-14 $0.94 231,800
2026-05-13 $0.88 241,000
2026-05-12 $0.90 71,800
2026-05-11 $0.93 112,200
2026-05-08 $0.98 974,500
2026-05-07 $0.88 314,400
2026-05-06 $0.83 181,600
About Aprea Therapeutics, Inc.

Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.

Period:
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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $0 $0 $0 $0
Operating Revenue $0 $0 $0 $0
Expenses
Total Expenses $13,233,836 $14,319,655 $15,471,963 $37,372,044
Other Income Expense $-17,819 $71,800 $-38,926 $-75,738,650
Other Non Operating Income Expenses $77,500 - - -
Net Non Operating Interest Income Expense $652,086 $1,289,144 $1,224,133 $448,667
Operating Expense $13,233,836 $14,319,655 $15,471,963 $37,372,044
Other Operating Expenses $-285,759 $-1,502,581 $-583,231 -
General And Administrative Expense $6,476,560 $6,458,699 $8,427,703 $20,969,771
Total Other Finance Cost - - - $-448,667
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Net Interest Income $652,086 $1,289,144 $1,224,133 $448,667
Interest Income $652,086 $1,289,144 $1,224,133 $448,667
Normalized Income $-12,504,250 $-13,030,511 $-14,247,830 $-36,923,377
Net Income From Continuing And Discontinued Operation $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Total Operating Income As Reported $-13,233,836 $-14,319,655 $-15,471,963 $-113,392,228
Net Income Common Stockholders $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Net Income $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Net Income Including Noncontrolling Interests $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Net Income Continuous Operations $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Pretax Income $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Interest Income Non Operating $652,086 $1,289,144 $1,224,133 $448,667
Operating Income $-13,233,836 $-14,319,655 $-15,471,963 $-37,372,044
Special Income Charges - - $0 $-76,020,184
Per Share
Diluted EPS - $-2.35 $-3.95 $-67.99
Basic EPS - $-2.35 $-3.95 $-67.99
Other
Tax Effect Of Unusual Items $0 $0 $0 $0
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-13,116,802 $-14,369,137 $-15,425,985 $38,553,051
Total Unusual Items $-95,319 $71,800 $-38,926 $-75,738,650
Total Unusual Items Excluding Goodwill $-95,319 $71,800 $-38,926 $-75,738,650
Reconciled Depreciation $21,715 $22,318 $7,052 $186,445
EBITDA (Bullshit earnings) $-13,212,121 $-14,297,337 $-15,464,911 $-37,185,599
EBIT $-13,233,836 $-14,319,655 $-15,471,963 $-37,372,044
Diluted NI Availto Com Stockholders $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Gain On Sale Of Security $-95,319 $71,800 $-38,926 $281,534
Research And Development $7,043,035 $9,363,537 $7,627,491 $16,402,273
Selling General And Administration $6,476,560 $6,458,699 $8,427,703 $20,969,771
Other Gand A $6,476,560 $6,458,699 $8,427,703 $20,969,771
Diluted Average Shares - $5,509,921 $3,617,607 $1,657,055
Basic Average Shares - $5,509,921 $3,617,607 $1,657,055
Other Special Charges - - - $76,020,184
Fetched: 2026-06-01
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $12,441,682 $19,307,455 $16,953,506 $25,643,678
Total Assets $15,933,401 $23,979,493 $22,650,174 $30,155,827
Total Non Current Assets $372,155 $403,354 $129,079 $2,321
Other Non Current Assets $312,348 $321,832 $40,717 -
Current Assets $15,561,246 $23,576,139 $22,521,095 $30,153,506
Other Current Assets $961,899 $726,254 $914,275 $1,366,859
Cash Cash Equivalents And Short Term Investments $14,599,347 $22,849,885 $21,606,820 $28,786,647
Cash And Cash Equivalents $14,599,347 $22,849,885 $21,606,820 $28,786,647
Prepaid Assets - - - -
Debt
Total Debt - - - $0
Long Term Debt And Capital Lease Obligation - - - $0
Current Debt And Capital Lease Obligation - - - -
Liabilities
Total Liabilities Net Minority Interest $3,491,719 $4,672,038 $5,696,668 $4,512,149
Total Non Current Liabilities Net Minority Interest $727,361 $1,311,063 $1,311,063 $1,311,063
Current Liabilities $2,764,358 $3,360,975 $4,385,605 $3,201,086
Payables And Accrued Expenses $1,993,796 $2,895,960 $2,839,671 $1,803,109
Payables $713,668 $1,352,240 $1,670,369 $842,754
Accounts Payable $713,668 $1,352,240 $1,670,369 $842,754
Current Deferred Liabilities - $0 $528,974 $0
Equity
Common Stock Equity $12,441,682 $19,307,455 $16,953,506 $25,643,678
Total Equity Gross Minority Interest $12,441,682 $19,307,455 $16,953,506 $25,643,678
Stockholders Equity $12,441,682 $19,307,455 $16,953,506 $25,643,678
Gains Losses Not Affecting Retained Earnings $-10,634,714 $-10,627,379 $-10,611,273 $-10,623,408
Other Equity Adjustments $-10,634,714 $-10,627,379 $-10,611,273 $-10,623,408
Retained Earnings $-333,641,441 $-321,041,872 $-308,083,161 $-293,796,405
Preferred Securities Outside Stock Equity $727,361 $1,311,063 $1,311,063 $1,311,063
Other
Ordinary Shares Number $8,192,538 $5,481,055 $3,736,673 $2,655,269
Share Issued $8,192,538 $5,481,055 $3,736,673 $2,655,269
Tangible Book Value $12,441,682 $19,307,455 $16,953,506 $25,643,678
Invested Capital $12,441,682 $19,307,455 $16,953,506 $25,643,678
Working Capital $12,796,888 $20,215,164 $18,135,490 $26,952,420
Total Capitalization $12,441,682 $19,307,455 $16,953,506 $25,643,678
Additional Paid In Capital $356,709,645 $350,971,225 $335,644,204 $330,060,836
Capital Stock $8,192 $5,481 $3,736 $2,655
Common Stock $8,192 $5,481 $3,736 $2,655
Pensionand Other Post Retirement Benefit Plans Current $770,562 $465,015 $1,016,960 $1,397,977
Current Accrued Expenses $1,280,128 $1,543,720 $1,169,302 $960,355
Net PPE $59,807 $81,522 $88,362 $2,321
Accumulated Depreciation $-94,155 $-72,440 $-50,122 $-43,070
Gross PPE $153,962 $153,962 $138,484 $45,391
Other Properties $148,704 $148,704 $133,226 $40,133
Machinery Furniture Equipment $5,258 $5,258 $5,258 $5,258
Current Deferred Revenue - $0 $528,974 $0
Capital Lease Obligations - - - $0
Long Term Capital Lease Obligation - - - $0
Current Capital Lease Obligation - - - $0
Fetched: 2026-06-01
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-12,894,439 $-13,572,196 $-12,270,701 $-25,011,136
Operating Activities
Operating Cash Flow $-12,894,439 $-13,556,718 $-12,177,608 $-25,011,136
Cash Flow From Continuing Operating Activities $-12,894,439 $-13,556,718 $-12,177,608 $-25,011,136
Operating Gains Losses $95,319 $-71,800 $38,926 $-281,534
Investing Activities
Investing Cash Flow $0 $-15,478 $-93,093 $0
Cash Flow From Continuing Investing Activities $0 $-15,478 $-93,093 $0
Capital Expenditure - $-15,478 $-93,093 -
Financing Activities
Issuance Of Capital Stock $5,047,606 $16,140,356 $5,788,918 $682,973
Financing Cash Flow $4,640,238 $14,821,895 $5,139,990 $682,973
Cash Flow From Continuing Financing Activities $4,640,238 $14,821,895 $5,139,990 $682,973
Net Other Financing Charges $-407,459 $-1,318,461 $-648,928 -
Net Common Stock Issuance $5,047,606 $16,140,356 $5,788,918 $682,973
Common Stock Issuance $5,047,606 $16,140,356 $5,788,918 $682,973
Net Preferred Stock Issuance - - - -
Preferred Stock Issuance - - - -
Other
End Cash Position $14,640,533 $22,890,055 $21,647,537 $28,786,647
Beginning Cash Position $22,890,055 $21,647,537 $28,786,647 $53,076,052
Effect Of Exchange Rate Changes $4,679 $-7,181 $-8,399 $38,758
Changes In Cash $-8,254,201 $1,249,699 $-7,130,711 $-24,328,163
Proceeds From Stock Option Exercised $91 $0 $0 $0
Net PPE Purchase And Sale $0 $-15,478 $-93,093 $0
Purchase Of PPE $0 $-15,478 $-93,093 $0
Change In Working Capital $-929,095 $-1,055,396 $1,618,711 $-1,758,579
Change In Payables And Accrued Expense $-711,189 $-429,748 $637,743 $-3,761,963
Change In Accrued Expense $-64,488 $-115,541 $-189,720 $-2,903,450
Change In Payable $-646,701 $-314,207 $827,463 $-858,513
Change In Account Payable $-646,701 $-314,207 $827,463 $-858,513
Change In Prepaid Assets $-217,906 $-96,674 $451,994 $2,190,086
Other Non Cash Items $39,050 $17,435 - $72,523,293
Stock Based Compensation $478,141 $489,436 $444,459 $16,981,266
Depreciation Amortization Depletion $21,715 $22,318 $7,052 $186,445
Depreciation And Amortization $21,715 $22,318 $7,052 $186,445
Net Foreign Currency Exchange Gain Loss $95,319 $-71,800 $38,926 $-281,534
Net Income From Continuing Operations $-12,599,569 $-12,958,711 $-14,286,756 $-112,662,027
Change In Other Working Capital - $-528,974 $528,974 -
Change In Other Current Liabilities - - $0 $-186,702
Depreciation - - $7,052 $186,445
Fetched: 2026-06-01