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CNTA

Centessa Pharmaceuticals plc

Price Chart
Latest Quote

$40.02

+0.15 (+0.38%)
Current Price
Previous Close $39.87
Open $39.83
Day High $40.07
Day Low $39.78
Volume 5,551,156
Fetched: 2026-06-19T11:08:35
Stock Information
Shares Outstanding 154.73M
Total Debt $118.56M
Cash Equivalents $276.59M
Net Income $-250.64M
Sector Healthcare
Industry Biotechnology
Market Cap $6.19B
EPS (TTM) $-1.78
Exchange NMS
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📊 Comprehensive Analysis
Company Data
Enterprise Value$5.99B
Income$-250.64M
Book/sh$3.15
Cash/sh$1.79
Employees129
Financial Ratios
Quick Ratio9.27
Current Ratio9.53
Debt/Eq24.33
Returns & Margins
ROA-27.43%
ROE-57.38%
Ownership
Insider Ownership0.51%
Institutional Ownership96.98%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E-22.37
P/B12.70
Analyst Data
Recommendationbuy
Target Price$44.17
Technical Indicators
SMA20$39.79
SMA50$39.66
SMA200$28.96
RSI62.04
ATR0.1825
Shares Float92.48M
Short Float1.96%
Short Ratio2.18
Volatility1.12
Rel Volume3.41
Performance History
Week+0.63%
Month+0.81%
Quarter+41.21%
6 Months+55.60%
YTD+68.93%
Year+217.62%
3 Years+755.13%
5 Years+84.34%
10 Years+84.00%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-18 $40.02 5,588,700
2026-06-17 $39.87 2,943,900
2026-06-16 $39.75 2,216,200
2026-06-15 $39.76 1,612,500
2026-06-12 $39.72 1,322,800
2026-06-11 $39.77 871,100
2026-06-10 $39.69 1,780,800
2026-06-09 $39.76 2,302,700
2026-06-08 $39.70 553,300
2026-06-05 $39.62 1,702,200
2026-06-04 $39.80 1,972,500
2026-06-03 $39.85 840,800
2026-06-02 $39.90 1,133,600
2026-06-01 $39.86 1,458,400
2026-05-29 $39.76 922,300
2026-05-28 $39.81 776,400
2026-05-27 $39.77 1,079,400
2026-05-26 $39.78 1,209,400
2026-05-22 $39.75 707,500
2026-05-21 $39.81 1,745,100
2026-05-20 $39.75 906,300
2026-05-19 $39.70 787,600
About Centessa Pharmaceuticals plc

Centessa Pharmaceuticals plc, together with its subsidiaries, discovers, develops, and delivers orexin-based neuroscience therapeutics in the United Kingdom and the United States. The company develops ORX750, an orexin receptor 2 agonist, which is in Phase IIa clinical trial for the treatment of central disorders of hypersomnolence, including narcolepsy type 1 and 2, as well as idiopathic hypersomnia. It also engages in the development of ORX142 which is in Phase I clinical trial for the treatment of neurological and neurodegenerative disorders; ORX489 which is in Phase I clinical trial for the treatment of neuropsychiatric disorders; and LockBody, an early-stage immuno-oncology program technology platform. The company was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.

Period:
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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $15,000,000 $0 $6,853,000 $0
Operating Revenue $15,000,000 $0 $6,853,000 $0
Expenses
Interest Expense $11,459,000 $10,090,000 $9,906,000 $7,277,000
Total Expenses $222,692,000 $201,055,000 $178,136,000 $210,283,000
Other Income Expense $2,911,000 $-35,784,000 $-5,428,000 $362,000
Other Non Operating Income Expenses $2,911,000 $-1,687,000 $-5,428,000 $2,342,000
Net Non Operating Interest Income Expense $9,068,000 $3,926,000 $570,000 $-7,033,000
Interest Expense Non Operating $11,459,000 $10,090,000 $9,906,000 $7,277,000
Operating Expense $222,692,000 $201,055,000 $178,136,000 $210,283,000
General And Administrative Expense $50,468,000 $50,811,000 $53,731,000 $55,200,000
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Net Interest Income $9,068,000 $3,926,000 $570,000 $-7,033,000
Interest Income $20,527,000 $14,016,000 $10,476,000 $244,000
Normalized Income $-197,532,000 $-210,184,250 $-151,085,000 $-214,233,817
Net Income From Continuing And Discontinued Operation $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Total Operating Income As Reported $-207,692,000 $-201,055,000 $-171,283,000 $-212,263,000
Net Income Common Stockholders $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Net Income $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Net Income Including Noncontrolling Interests $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Net Income Continuous Operations $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Pretax Income $-195,713,000 $-232,913,000 $-176,141,000 $-216,954,000
Special Income Charges $0 $-34,097,000 $0 $-1,980,000
Interest Income Non Operating $20,527,000 $14,016,000 $10,476,000 $244,000
Operating Income $-207,692,000 $-201,055,000 $-171,283,000 $-210,283,000
Per Share
Diluted EPS $-1.46 $-2.06 $-1.57 $-2.31
Basic EPS $-1.46 $-2.06 $-1.57 $-2.31
Other
Tax Effect Of Unusual Items $0 $-8,524,250 $0 $-6,817
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-183,333,000 $-187,784,000 $-165,425,000 $-207,566,000
Total Unusual Items $0 $-34,097,000 $0 $-1,980,000
Total Unusual Items Excluding Goodwill $0 $-34,097,000 $0 $-1,980,000
Reconciled Depreciation $921,000 $942,000 $810,000 $131,000
EBITDA (Bullshit earnings) $-183,333,000 $-221,881,000 $-165,425,000 $-209,546,000
EBIT $-184,254,000 $-222,823,000 $-166,235,000 $-209,677,000
Diluted Average Shares $135,715,608 $114,473,449 $96,177,578 $93,400,513
Basic Average Shares $135,715,608 $114,473,449 $96,177,578 $93,400,513
Diluted NI Availto Com Stockholders $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Tax Provision $1,819,000 $2,844,000 $-25,056,000 $-747,000
Research And Development $172,224,000 $150,244,000 $124,405,000 $155,083,000
Selling General And Administration $50,468,000 $50,811,000 $53,731,000 $55,200,000
Other Gand A $21,082,000 $19,914,000 $26,106,000 $29,279,000
Salaries And Wages $29,386,000 $30,897,000 $27,625,000 $25,921,000
Other Special Charges - $34,097,000 - -
Restructuring And Mergern Acquisition - - $0 $1,980,000
Fetched: 2026-06-08
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $526,863,000 $401,545,000 $236,244,000 $336,169,000
Total Assets $687,495,000 $576,798,000 $360,246,000 $444,307,000
Total Non Current Assets $319,620,000 $40,389,000 $45,154,000 $6,560,000
Other Non Current Assets $1,440,000 $2,046,000 $2,554,000 $1,880,000
Non Current Deferred Assets $24,778,000 $26,586,000 $29,647,000 $3,512,000
Non Current Deferred Taxes Assets $24,778,000 $26,586,000 $29,647,000 $3,512,000
Current Assets $367,875,000 $536,409,000 $315,092,000 $437,747,000
Other Current Assets $1,827,000 $1,495,000 $1,621,000 $3,271,000
Prepaid Assets $11,127,000 $7,154,000 $17,774,000 $14,109,000
Receivables $60,341,000 $45,583,000 $39,148,000 $26,723,000
Taxes Receivable $56,981,000 $45,296,000 $39,148,000 $26,723,000
Accrued Interest Receivable $3,360,000 $287,000 - -
Cash Cash Equivalents And Short Term Investments $294,580,000 $482,177,000 $256,549,000 $393,644,000
Cash And Cash Equivalents $61,299,000 $383,221,000 $128,030,000 $393,644,000
Debt
Net Debt $48,796,000 - - -
Total Debt $118,381,000 $117,828,000 $84,588,000 $69,800,000
Long Term Debt And Capital Lease Obligation $117,668,000 $117,226,000 $84,588,000 $69,800,000
Long Term Debt $110,095,000 $108,940,000 $75,700,000 $69,800,000
Current Debt And Capital Lease Obligation $713,000 $602,000 - -
Liabilities
Total Liabilities Net Minority Interest $160,632,000 $175,253,000 $124,002,000 $108,138,000
Total Non Current Liabilities Net Minority Interest $117,697,000 $117,255,000 $84,617,000 $69,800,000
Other Non Current Liabilities $29,000 $29,000 $29,000 -
Current Liabilities $42,935,000 $57,998,000 $39,385,000 $38,338,000
Other Current Liabilities $217,000 $108,000 $839,000 $690,000
Payables And Accrued Expenses $27,538,000 $47,823,000 $31,813,000 $30,384,000
Interest Payable $840,000 $0 - -
Payables $7,582,000 $7,978,000 $11,927,000 $15,418,000
Total Tax Payable $0 $835,000 $112,000 $1,582,000
Income Tax Payable $0 $835,000 $112,000 $1,582,000
Accounts Payable $7,582,000 $7,143,000 $11,815,000 $13,836,000
Derivative Product Liabilities - - - -
Equity
Common Stock Equity $526,863,000 $401,545,000 $236,244,000 $336,169,000
Total Equity Gross Minority Interest $526,863,000 $401,545,000 $236,244,000 $336,169,000
Stockholders Equity $526,863,000 $401,545,000 $236,244,000 $336,169,000
Gains Losses Not Affecting Retained Earnings $2,714,000 $4,213,000 $1,493,000 $-1,497,000
Other Equity Adjustments $2,714,000 $4,213,000 $1,493,000 $-1,497,000
Retained Earnings $-1,186,234,000 $-988,702,000 $-752,945,000 $-601,860,000
Preferred Securities Outside Stock Equity - - - -
Other
Ordinary Shares Number $149,228,068 $132,631,587 $98,774,827 $94,843,391
Share Issued $149,228,068 $132,631,587 $98,774,827 $94,843,391
Tangible Book Value $526,863,000 $401,545,000 $236,244,000 $336,169,000
Invested Capital $636,958,000 $510,485,000 $311,944,000 $405,969,000
Working Capital $324,940,000 $478,411,000 $275,707,000 $399,409,000
Capital Lease Obligations $8,286,000 $8,888,000 $8,888,000 $0
Total Capitalization $636,958,000 $510,485,000 $311,944,000 $405,969,000
Additional Paid In Capital $1,709,978,000 $1,385,675,000 $987,423,000 $939,261,000
Capital Stock $405,000 $359,000 $273,000 $265,000
Common Stock $405,000 $359,000 $273,000 $265,000
Long Term Capital Lease Obligation $7,573,000 $8,286,000 $8,888,000 $0
Current Capital Lease Obligation $713,000 $602,000 - -
Pensionand Other Post Retirement Benefit Plans Current $14,467,000 $9,465,000 $6,733,000 $7,264,000
Current Accrued Expenses $19,956,000 $39,845,000 $19,886,000 $14,966,000
Investments And Advances $282,548,000 $0 - -
Net PPE $10,854,000 $11,757,000 $12,953,000 $1,168,000
Accumulated Depreciation $-1,099,000 $-791,000 $-462,000 $-164,000
Gross PPE $11,953,000 $12,548,000 $13,415,000 $1,332,000
Machinery Furniture Equipment $1,906,000 $1,535,000 $1,501,000 $442,000
Buildings And Improvements $10,047,000 $11,013,000 $11,914,000 -
Properties $0 $0 $0 -
Other Short Term Investments $233,281,000 $98,956,000 $128,519,000 $0
Construction In Progress - - $0 $890,000
Preferred Stock - - - -
Line Of Credit - - - -
Fetched: 2026-06-08
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-194,188,000 $-142,089,000 $-160,511,000 $-201,683,000
Operating Activities
Operating Cash Flow $-193,817,000 $-142,055,000 $-160,342,000 $-200,546,000
Cash Flow From Continuing Operating Activities $-193,817,000 $-142,055,000 $-160,342,000 $-200,546,000
Operating Gains Losses - $34,097,000 - -
Investing Activities
Capital Expenditure $-371,000 $-34,000 $-169,000 $-1,137,000
Investing Cash Flow $-418,531,000 $31,267,000 $-127,004,000 $-931,000
Cash Flow From Continuing Investing Activities $-418,531,000 $31,267,000 $-127,004,000 $-931,000
Net Other Investing Changes - - - $206,000
Financing Activities
Issuance Of Capital Stock $275,358,000 $359,605,000 $20,807,000 $0
Financing Cash Flow $291,528,000 $364,752,000 $21,117,000 $457,000
Cash Flow From Continuing Financing Activities $291,528,000 $364,752,000 $21,117,000 $457,000
Net Other Financing Charges $-5,192,000 $-5,318,000 - $-261,000
Net Common Stock Issuance $275,358,000 $359,605,000 $20,807,000 $0
Common Stock Issuance $275,358,000 $359,605,000 $20,807,000 $0
Net Preferred Stock Issuance - - - $0
Preferred Stock Issuance - - - $0
Other
Repayment Of Debt $0 $-110,097,000 $0 -
Issuance Of Debt $0 $109,335,000 $0 $0
Interest Paid Supplemental Data $9,464,000 $10,085,000 $9,906,000 $7,277,000
Income Tax Paid Supplemental Data $1,331,000 $82,000 $2,943,000 $1,299,000
End Cash Position $61,953,000 $383,221,000 $128,030,000 $393,644,000
Beginning Cash Position $383,221,000 $128,030,000 $393,644,000 $595,082,000
Effect Of Exchange Rate Changes $-448,000 $1,227,000 $615,000 $-418,000
Changes In Cash $-320,820,000 $253,964,000 $-266,229,000 $-201,020,000
Proceeds From Stock Option Exercised $21,362,000 $11,227,000 $310,000 $718,000
Net Issuance Payments Of Debt $0 $-762,000 $0 $0
Net Long Term Debt Issuance $0 $-762,000 $0 $0
Long Term Debt Payments $0 $-110,097,000 $0 -
Long Term Debt Issuance $0 $109,335,000 $0 $0
Net Investment Purchase And Sale $-418,160,000 $31,301,000 $-126,835,000 $0
Sale Of Investment $321,601,000 $171,834,000 $138,075,000 $0
Purchase Of Investment $-739,761,000 $-140,533,000 $-264,910,000 $0
Net PPE Purchase And Sale $-371,000 $-34,000 $-169,000 $-1,137,000
Purchase Of PPE $-371,000 $-34,000 $-169,000 $-1,137,000
Change In Working Capital $-30,022,000 $22,102,000 $-18,858,000 $-2,831,000
Change In Other Current Assets $253,000 $298,000 $-1,883,000 $0
Change In Payables And Accrued Expense $-15,166,000 $18,186,000 $-3,519,000 $12,612,000
Change In Accrued Expense $-15,216,000 $22,771,000 $-797,000 $6,261,000
Change In Payable $50,000 $-4,585,000 $-2,722,000 $6,351,000
Change In Account Payable $50,000 $-4,585,000 $-2,722,000 $6,351,000
Change In Prepaid Assets $-7,852,000 $10,219,000 $-1,364,000 $-3,732,000
Change In Receivables $-7,257,000 $-6,601,000 $-12,092,000 $-11,711,000
Other Non Cash Items $1,147,000 $62,000 $28,000 $173,000
Stock Based Compensation $30,962,000 $33,546,000 $29,392,000 $24,965,000
Unrealized Gain Loss On Investment Securities $0 $300,000 $5,900,000 $-3,920,000
Amortization Of Securities $-1,802,000 $0 - -
Deferred Tax $2,509,000 $2,653,000 $-26,529,000 $-2,857,000
Deferred Income Tax $2,509,000 $2,653,000 $-26,529,000 $-2,857,000
Depreciation Amortization Depletion $921,000 $942,000 $810,000 $131,000
Depreciation And Amortization $921,000 $942,000 $810,000 $131,000
Net Income From Continuing Operations $-197,532,000 $-235,757,000 $-151,085,000 $-216,207,000
Net Business Purchase And Sale - - - $0
Sale Of Business - - - $0
Fetched: 2026-06-08