FULC
Fulcrum Therapeutics, Inc.
Price Chart
Latest Quote
$3.83
| Previous Close | $3.77 |
| Open | $3.69 |
| Day High | $3.89 |
| Day Low | $3.69 |
| Volume | 1,372,008 |
Stock Information
| Shares Outstanding | 66.63M |
| Total Debt | $5.87M |
| Cash Equivalents | $333.32M |
| Net Income | $-76.12M |
| Sector | Healthcare |
| Industry | Biotechnology |
| Market Cap | $255.21M |
| EPS (TTM) | $-1.15 |
| Exchange | NGM |
đ Comprehensive Analysis
Company Data
| Enterprise Value | $-76.24M |
| Income | $-76.12M |
| Book/sh | $5.00 |
| Cash/sh | $5.00 |
| Employees | 55 |
Financial Ratios
| Quick Ratio | 33.97 |
| Current Ratio | 34.33 |
| Debt/Eq | 1.76 |
Returns & Margins
| ROA | -18.36% |
| ROE | -27.10% |
Ownership
| Insider Ownership | 3.86% |
| Institutional Ownership | 116.30% |
| Insider & Institutional transactions data not available | |
Valuation Ratios
| Forward P/E | -5.82 |
| P/B | 0.77 |
Analyst Data
| Recommendation | hold |
| Target Price | $5.43 |
Technical Indicators
| SMA20 | $4.32 |
| SMA50 | $6.08 |
| SMA200 | $8.57 |
| RSI | 72.85 |
| ATR | 0.2304 |
| Shares Float | 47.97M |
| Short Float | 12.14% |
| Short Ratio | 14.73 |
| Volatility | 2.92 |
| Rel Volume | 0.29 |
Performance History
| Week | +9.12% |
| Month | -41.88% |
| Quarter | -44.41% |
| 6 Months | -68.50% |
| YTD | -64.93% |
| Year | -45.25% |
| 3 Years | +25.99% |
| 5 Years | -54.62% |
| 10 Years | -71.63% |
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Recent Price History
| Date | Close | Volume |
|---|---|---|
| 2026-06-23 | $3.83 | 1,372,008 |
| 2026-06-22 | $3.77 | 2,868,500 |
| 2026-06-18 | $3.70 | 6,100,800 |
| 2026-06-17 | $3.50 | 10,467,900 |
| 2026-06-16 | $3.46 | 6,026,500 |
| 2026-06-15 | $3.51 | 3,335,000 |
| 2026-06-12 | $3.45 | 1,344,100 |
| 2026-06-11 | $3.55 | 2,500,300 |
| 2026-06-10 | $3.51 | 2,459,500 |
| 2026-06-09 | $3.52 | 3,984,900 |
| 2026-06-08 | $3.44 | 3,314,200 |
| 2026-06-05 | $3.69 | 3,955,400 |
| 2026-06-04 | $3.37 | 4,816,200 |
| 2026-06-03 | $3.22 | 5,598,700 |
| 2026-06-02 | $3.14 | 32,803,600 |
| 2026-06-01 | $6.42 | 3,121,500 |
| 2026-05-29 | $6.92 | 391,000 |
| 2026-05-28 | $6.82 | 313,600 |
| 2026-05-27 | $6.78 | 326,000 |
| 2026-05-26 | $6.76 | 369,200 |
About Fulcrum Therapeutics, Inc.
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
đ° Latest News
A Look At Fulcrum Therapeutics (FULC) Valuation After Scrapping Lead Sickle Cell Drug And Restructuring
Simply Wall St. âĸ 2026-06-05T15:15:30ZFulcrum Therapeutics (FULC) Loses 51% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner
Zacks âĸ 2026-06-05T13:35:02ZFULC Stock Crashes as Cancer Risk Forces Its Only Drug Program's End
Zacks âĸ 2026-06-03T15:00:00ZWhy Did FULC, MVIS, HRTX Stocks Plunge To 52-Week Lows Today?
Stocktwits âĸ 2026-06-03T03:04:14ZThis Biotech Stock Plunges 54%. Its Sickle Cell Drug Has âNo Viable Path Forward.â
Barrons.com âĸ 2026-06-02T16:13:00ZMeta Platforms upgraded, Okta downgraded: Wall Street's top analyst calls
The Fly âĸ 2026-06-02T13:43:12ZFulcrum exploring a potential sale after FDA sidelined its sickle cell drug
BioPharma Dive âĸ 2026-06-02T12:08:00ZFULC Stock Slumps Nearly 50% After Hours As FDA Kills Only Clinical Program Over Cancer Risk
Stocktwits âĸ 2026-06-01T21:50:50ZFulcrum Therapeutics Discontinues Sickle Cell Disease Program After US FDA Raises Malignancy Concerns
MT Newswires âĸ 2026-06-01T20:56:27ZAfter Plunging 21.5% in 4 Weeks, Here's Why the Trend Might Reverse for Fulcrum Therapeutics (FULC)
Zacks âĸ 2026-05-20T13:35:03ZIncome Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Revenue | ||||
| Total Revenue | $0 | $80,000,000 | $2,805,000 | $6,342,000 |
| Operating Revenue | $0 | $80,000,000 | $2,805,000 | $6,342,000 |
| Expenses | ||||
| Total Expenses | $84,769,000 | $99,834,000 | $113,469,000 | $118,476,000 |
| Other Income Expense | $9,889,000 | $10,109,000 | $13,329,000 | $2,263,000 |
| Other Non Operating Income Expenses | $9,889,000 | $12,172,000 | $13,329,000 | $2,690,000 |
| Operating Expense | $84,769,000 | $99,834,000 | $113,469,000 | $118,476,000 |
| General And Administrative Expense | $28,666,000 | $36,448,000 | $41,668,000 | $41,694,000 |
| Income & Earnings | ||||
| Net Income From Continuing Operation Net Minority Interest | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Normalized Income | $-74,880,000 | $-7,662,000 | $-97,335,000 | $-109,444,000 |
| Net Income From Continuing And Discontinued Operation | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Total Operating Income As Reported | $-84,769,000 | $-21,897,000 | $-110,664,000 | $-112,561,000 |
| Net Income Common Stockholders | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Net Income | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Net Income Including Noncontrolling Interests | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Net Income Continuous Operations | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Pretax Income | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Special Income Charges | $0 | $-2,063,000 | $0 | $-427,000 |
| Operating Income | $-84,769,000 | $-19,834,000 | $-110,664,000 | $-112,134,000 |
| Per Share | ||||
| Diluted EPS | $-1.18 | $-0.16 | $-1.59 | $-2.44 |
| Basic EPS | $-1.18 | $-0.16 | $-1.59 | $-2.44 |
| Other | ||||
| Tax Effect Of Unusual Items | $0 | $0 | $0 | $0 |
| Tax Rate For Calcs | $0 | $0 | $0 | $0 |
| Normalized EBITDA (Bullshit earnings) | $-83,379,000 | $-16,178,000 | $-108,492,000 | $-109,293,000 |
| Total Unusual Items | $0 | $-2,063,000 | $0 | $-427,000 |
| Total Unusual Items Excluding Goodwill | $0 | $-2,063,000 | $0 | $-427,000 |
| Reconciled Depreciation | $1,390,000 | $1,593,000 | $2,172,000 | $2,414,000 |
| EBITDA (Bullshit earnings) | $-83,379,000 | $-18,241,000 | $-108,492,000 | $-109,720,000 |
| EBIT | $-84,769,000 | $-19,834,000 | $-110,664,000 | $-112,134,000 |
| Diluted Average Shares | $63,355,000 | $61,984,000 | $61,310,000 | $44,991,000 |
| Basic Average Shares | $63,355,000 | $61,984,000 | $61,310,000 | $44,991,000 |
| Diluted NI Availto Com Stockholders | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,871,000 |
| Restructuring And Mergern Acquisition | $0 | $2,063,000 | $0 | $427,000 |
| Research And Development | $56,103,000 | $63,386,000 | $71,801,000 | $76,782,000 |
| Selling General And Administration | $28,666,000 | $36,448,000 | $41,668,000 | $41,694,000 |
| Other Gand A | $11,338,000 | $16,694,000 | $16,859,000 | $18,206,000 |
| Salaries And Wages | $17,328,000 | $19,754,000 | $24,809,000 | $23,488,000 |
Balance Sheet (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Assets | ||||
| Net Tangible Assets | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Total Assets | $366,284,000 | $260,718,000 | $257,694,000 | $226,685,000 |
| Total Non Current Assets | $8,804,000 | $10,795,000 | $15,495,000 | $19,166,000 |
| Other Non Current Assets | $1,739,000 | $1,211,000 | $3,103,000 | $3,197,000 |
| Current Assets | $357,480,000 | $249,923,000 | $242,199,000 | $207,519,000 |
| Prepaid Assets | $4,104,000 | $5,560,000 | $3,729,000 | $3,517,000 |
| Receivables | $1,070,000 | $3,342,000 | $2,249,000 | $1,081,000 |
| Accrued Interest Receivable | $1,070,000 | $1,246,000 | $1,712,000 | $852,000 |
| Cash Cash Equivalents And Short Term Investments | $352,306,000 | $241,021,000 | $236,221,000 | $202,921,000 |
| Cash And Cash Equivalents | $197,533,000 | $58,212,000 | $25,563,000 | $35,098,000 |
| Cash Equivalents | $197,533,000 | $58,212,000 | $25,563,000 | $35,098,000 |
| Other Receivables | - | $2,096,000 | $537,000 | $229,000 |
| Accounts Receivable | - | - | - | $0 |
| Debt | ||||
| Total Debt | $6,443,000 | $8,629,000 | $10,821,000 | $13,423,000 |
| Long Term Debt And Capital Lease Obligation | $4,039,000 | $6,443,000 | $8,629,000 | $10,821,000 |
| Current Debt And Capital Lease Obligation | $2,404,000 | $2,186,000 | $2,192,000 | $2,602,000 |
| Liabilities | ||||
| Total Liabilities Net Minority Interest | $17,284,000 | $17,684,000 | $22,501,000 | $27,743,000 |
| Total Non Current Liabilities Net Minority Interest | $4,236,000 | $6,640,000 | $8,826,000 | $11,018,000 |
| Other Non Current Liabilities | $197,000 | $197,000 | $197,000 | $197,000 |
| Current Liabilities | $13,048,000 | $11,044,000 | $13,675,000 | $16,725,000 |
| Other Current Liabilities | $258,000 | $463,000 | $396,000 | $105,000 |
| Payables And Accrued Expenses | $10,386,000 | $8,395,000 | $11,087,000 | $13,084,000 |
| Payables | $1,592,000 | $1,164,000 | $2,757,000 | $3,638,000 |
| Accounts Payable | $1,592,000 | $1,164,000 | $2,757,000 | $3,638,000 |
| Current Deferred Liabilities | - | - | $0 | $934,000 |
| Non Current Deferred Liabilities | - | - | - | $0 |
| Equity | ||||
| Common Stock Equity | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Total Equity Gross Minority Interest | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Stockholders Equity | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Gains Losses Not Affecting Retained Earnings | $174,000 | $130,000 | $-136,000 | $-797,000 |
| Other Equity Adjustments | $174,000 | $130,000 | $-136,000 | $-797,000 |
| Retained Earnings | $-594,278,000 | $-519,398,000 | $-509,673,000 | $-412,338,000 |
| Other | ||||
| Ordinary Shares Number | $66,578,891 | $53,968,303 | $61,915,367 | $52,099,211 |
| Share Issued | $66,578,891 | $53,968,303 | $61,915,367 | $52,099,211 |
| Tangible Book Value | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Invested Capital | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Working Capital | $344,432,000 | $238,879,000 | $228,524,000 | $190,794,000 |
| Capital Lease Obligations | $6,443,000 | $8,629,000 | $10,821,000 | $13,423,000 |
| Total Capitalization | $349,000,000 | $243,034,000 | $235,193,000 | $198,942,000 |
| Additional Paid In Capital | $943,037,000 | $762,248,000 | $744,940,000 | $612,025,000 |
| Capital Stock | $67,000 | $54,000 | $62,000 | $52,000 |
| Common Stock | $67,000 | $54,000 | $62,000 | $52,000 |
| Preferred Stock | $0 | $0 | $0 | $0 |
| Long Term Capital Lease Obligation | $4,039,000 | $6,443,000 | $8,629,000 | $10,821,000 |
| Current Capital Lease Obligation | $2,404,000 | $2,186,000 | $2,192,000 | $2,602,000 |
| Current Accrued Expenses | $8,794,000 | $7,231,000 | $8,330,000 | $9,446,000 |
| Net PPE | $7,065,000 | $9,584,000 | $12,392,000 | $15,969,000 |
| Accumulated Depreciation | $-15,647,000 | $-14,257,000 | $-12,760,000 | $-10,662,000 |
| Gross PPE | $22,712,000 | $23,841,000 | $25,152,000 | $26,631,000 |
| Leases | $7,121,000 | $7,121,000 | $7,102,000 | $7,102,000 |
| Other Properties | $14,399,000 | $15,528,000 | $16,858,000 | $18,120,000 |
| Machinery Furniture Equipment | $1,192,000 | $1,192,000 | $1,192,000 | $1,378,000 |
| Properties | $0 | $0 | $0 | $0 |
| Other Short Term Investments | $154,773,000 | $182,809,000 | $210,658,000 | $167,823,000 |
| Treasury Shares Number | - | - | $0 | - |
| Current Deferred Revenue | - | - | $0 | $934,000 |
| Construction In Progress | - | - | $0 | $31,000 |
| Treasury Stock | - | - | - | $0 |
| Non Current Deferred Revenue | - | - | - | $0 |
Cash Flow Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Free Cash Flow | ||||
| Free Cash Flow | $-60,379,000 | $-2,496,000 | $-91,473,000 | $-99,013,000 |
| Operating Activities | ||||
| Operating Cash Flow | $-60,065,000 | $-2,218,000 | $-90,965,000 | $-97,050,000 |
| Cash Flow From Continuing Operating Activities | $-60,065,000 | $-2,218,000 | $-90,965,000 | $-97,050,000 |
| Investing Activities | ||||
| Capital Expenditure | $-314,000 | $-278,000 | $-508,000 | $-1,963,000 |
| Investing Cash Flow | $30,719,000 | $32,230,000 | $-36,692,000 | $12,413,000 |
| Cash Flow From Continuing Investing Activities | $30,719,000 | $32,230,000 | $-36,692,000 | $12,413,000 |
| Financing Activities | ||||
| Issuance Of Capital Stock | $164,500,000 | $0 | $117,345,000 | $80,804,000 |
| Financing Cash Flow | $168,667,000 | $2,746,000 | $118,122,000 | $84,323,000 |
| Cash Flow From Continuing Financing Activities | $168,667,000 | $2,746,000 | $118,122,000 | $84,323,000 |
| Net Common Stock Issuance | $164,500,000 | $0 | $117,345,000 | $80,804,000 |
| Common Stock Issuance | $164,500,000 | $0 | $117,345,000 | $80,804,000 |
| Other | ||||
| End Cash Position | $198,734,000 | $59,413,000 | $26,655,000 | $36,190,000 |
| Beginning Cash Position | $59,413,000 | $26,655,000 | $36,190,000 | $36,504,000 |
| Changes In Cash | $139,321,000 | $32,758,000 | $-9,535,000 | $-314,000 |
| Proceeds From Stock Option Exercised | $4,167,000 | $2,746,000 | $777,000 | $3,519,000 |
| Net Investment Purchase And Sale | $31,033,000 | $32,508,000 | $-36,184,000 | $14,376,000 |
| Sale Of Investment | $211,253,000 | $211,102,000 | $158,708,000 | $165,529,000 |
| Purchase Of Investment | $-180,220,000 | $-178,594,000 | $-194,892,000 | $-151,153,000 |
| Net PPE Purchase And Sale | $-314,000 | $-278,000 | $-508,000 | $-1,963,000 |
| Purchase Of PPE | $-314,000 | $-278,000 | $-508,000 | $-1,963,000 |
| Change In Working Capital | $3,910,000 | $-4,248,000 | $-4,613,000 | $-3,094,000 |
| Change In Other Working Capital | $-743,000 | $-700,000 | $-1,649,000 | $-4,149,000 |
| Change In Other Current Assets | $-528,000 | $2,001,000 | $94,000 | $-1,562,000 |
| Change In Payables And Accrued Expense | $1,453,000 | $-2,625,000 | $-1,678,000 | $-621,000 |
| Change In Accrued Expense | $1,025,000 | $-1,032,000 | $-825,000 | $555,000 |
| Change In Payable | $428,000 | $-1,593,000 | $-853,000 | $-1,176,000 |
| Change In Account Payable | $428,000 | $-1,593,000 | $-853,000 | $-1,176,000 |
| Change In Prepaid Assets | $1,632,000 | $-1,365,000 | $-1,072,000 | $-170,000 |
| Change In Receivables | $2,096,000 | $-1,559,000 | $-308,000 | $3,408,000 |
| Stock Based Compensation | $12,468,000 | $14,554,000 | $14,802,000 | $13,350,000 |
| Amortization Of Securities | $-2,953,000 | $-4,392,000 | $-5,991,000 | $152,000 |
| Depreciation Amortization Depletion | $1,390,000 | $1,593,000 | $2,172,000 | $2,414,000 |
| Depreciation And Amortization | $1,390,000 | $1,593,000 | $2,172,000 | $2,414,000 |
| Depreciation | $1,390,000 | $1,593,000 | $2,172,000 | $2,414,000 |
| Net Income From Continuing Operations | $-74,880,000 | $-9,725,000 | $-97,335,000 | $-109,872,000 |
| Changes In Account Receivables | - | - | $0 | $2,500,000 |
| Repayment Of Debt | - | - | - | $0 |
| Net Issuance Payments Of Debt | - | - | - | $0 |
| Net Long Term Debt Issuance | - | - | - | $0 |
| Long Term Debt Payments | - | - | - | $0 |
| Interest Paid Supplemental Data | - | - | - | - |