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KRYS

Krystal Biotech, Inc.

Price Chart
Latest Quote

$347.63

+7.42 (+2.18%)
Current Price
Previous Close $340.21
Open $343.59
Day High $353.89
Day Low $343.59
Volume 354,253
Fetched: 2026-06-25T11:36:10
Stock Information
Shares Outstanding 29.48M
Total Debt $9.11M
Cash Equivalents $823.40M
Revenue $417.30M
Net Income $225.03M
Sector Healthcare
Industry Biotechnology
Market Cap $10.61B
P/E Ratio 48.12
EPS (TTM) $7.48
Exchange NMS
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📊 Comprehensive Analysis
Company Data
Enterprise Value$9.43B
Sales$417.30M
Income$225.03M
Book/sh$43.37
Cash/sh$27.93
Employees295
Financial Ratios
Quick Ratio8.82
Current Ratio9.46
Debt/Eq0.71
EPS Growth TTM56.50%
Returns & Margins
ROA9.04%
ROE19.90%
Gross Margin94.17%
Operating Margin46.14%
Profit Margin53.92%
Ownership
Insider Ownership10.97%
Institutional Ownership99.36%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E35.72
P/S25.43
P/B8.30
Analyst Data
Recommendationstrong_buy
Target Price$349.78
Technical Indicators
SMA20$320.69
SMA50$300.76
SMA200$248.17
RSI78.54
ATR12.9803
Shares Float23.42M
Short Float17.53%
Short Ratio10.55
Volatility0.53
Rel Volume0.99
Performance History
Week+5.35%
Month+18.91%
Quarter+41.18%
6 Months+44.20%
YTD+45.77%
Year+150.53%
3 Years+188.47%
5 Years+466.91%
10 Years+3282.80%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-25 $359.93 329,642
2026-06-24 $347.63 378,300
2026-06-23 $340.21 272,700
2026-06-22 $343.43 411,600
2026-06-18 $348.06 811,400
2026-06-17 $341.66 514,600
2026-06-16 $323.37 328,900
2026-06-15 $324.75 263,500
2026-06-12 $317.97 302,300
2026-06-11 $321.55 477,400
2026-06-10 $312.41 301,900
2026-06-09 $309.75 233,100
2026-06-08 $301.76 259,700
2026-06-05 $301.00 264,400
2026-06-04 $307.79 264,900
2026-06-03 $301.82 240,400
2026-06-02 $293.21 334,000
2026-06-01 $298.10 262,900
2026-05-29 $309.03 226,300
2026-05-28 $310.30 174,000
2026-05-27 $306.63 144,300
2026-05-26 $302.68 181,900
About Krystal Biotech, Inc.

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Reconciled Cost Of Revenue $23,049,000 $20,061,000 $3,094,000 $0
Cost Of Revenue $23,049,000 $20,061,000 $3,094,000 $0
Total Revenue $389,130,000 $290,515,000 $50,699,000 $0
Operating Revenue $389,130,000 $290,515,000 $50,699,000 $0
Expenses
Total Expenses $227,835,000 $187,267,000 $147,816,000 $120,196,000
Net Non Operating Interest Income Expense $28,176,000 $29,608,000 $22,514,000 $5,221,000
Operating Expense $204,786,000 $167,206,000 $144,722,000 $120,196,000
Other Income Expense - $-37,500,000 $87,500,000 $-25,000,000
Interest Expense - - $0 $0
Interest Expense Non Operating - - $0 $0
General And Administrative Expense - - - $77,735,000
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Net Interest Income $28,176,000 $29,608,000 $22,514,000 $5,221,000
Interest Income $28,176,000 $29,608,000 $22,514,000 $5,221,000
Normalized Income $204,831,000 $124,221,948 $-63,236,411 $-114,975,000
Net Income From Continuing And Discontinued Operation $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Total Operating Income As Reported $161,295,000 $65,748,000 $-109,617,000 $-145,196,000
Net Income Common Stockholders $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Net Income $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Net Income Including Noncontrolling Interests $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Net Income Continuous Operations $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Pretax Income $189,471,000 $95,356,000 $12,897,000 $-139,975,000
Special Income Charges $0 $-37,500,000 $87,500,000 $-25,000,000
Interest Income Non Operating $28,176,000 $29,608,000 $22,514,000 $5,221,000
Operating Income $161,295,000 $103,248,000 $-97,117,000 $-120,196,000
Gross Profit $366,081,000 $270,454,000 $47,605,000 $0
Per Share
Diluted EPS $6.84 $3.00 $0.39 $-5.49
Basic EPS $7.08 $3.12 $0.40 $-5.49
Other
Tax Effect Of Unusual Items $0 $-2,437,052 $13,331,589 $0
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $167,846,000 $147,462,000 $-178,706,000 $-91,811,000
Total Unusual Items $0 $-37,500,000 $87,500,000 $-25,000,000
Total Unusual Items Excluding Goodwill $0 $-37,500,000 $87,500,000 $-25,000,000
Reconciled Depreciation $6,551,000 $6,714,000 $5,911,000 $3,385,000
EBITDA (Bullshit earnings) $167,846,000 $109,962,000 $-91,206,000 $-116,811,000
EBIT $161,295,000 $103,248,000 $-97,117,000 $-120,196,000
Diluted Average Shares $29,951,000 $29,740,000 $27,752,000 $25,492,000
Basic Average Shares $28,944,000 $28,592,000 $27,154,000 $25,492,000
Diluted NI Availto Com Stockholders $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Tax Provision $-15,360,000 $6,197,000 $1,965,000 $0
Research And Development $58,045,000 $53,580,000 $46,433,000 $42,461,000
Selling General And Administration $146,741,000 $113,626,000 $98,289,000 $77,735,000
Other Special Charges - $37,500,000 $-87,500,000 $25,000,000
Other Gand A - - - $77,735,000
Fetched: 2026-06-18
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Total Assets $1,333,794,000 $1,055,838,000 $818,355,000 $558,450,000
Total Non Current Assets $309,192,000 $313,793,000 $230,446,000 $174,671,000
Other Non Current Assets $287,000 $231,000 $263,000 $324,000
Non Current Deferred Assets $22,824,000 $0 - -
Non Current Deferred Taxes Assets $22,824,000 $0 - -
Investmentin Financial Assets $128,066,000 $152,114,000 $61,954,000 $4,621,000
Current Assets $1,024,602,000 $742,045,000 $587,909,000 $383,779,000
Other Current Assets $14,905,000 $11,657,000 $6,706,000 $4,608,000
Prepaid Assets $14,006,000 $1,617,000 - -
Inventory $40,475,000 $26,508,000 $6,985,000 $0
Receivables $127,425,000 $104,746,000 $42,040,000 $0
Accounts Receivable $127,425,000 $104,746,000 $42,040,000 $0
Cash Cash Equivalents And Short Term Investments $827,791,000 $597,517,000 $532,178,000 $379,171,000
Cash And Cash Equivalents $496,304,000 $344,865,000 $358,328,000 $161,900,000
Debt
Total Debt $9,339,000 $7,261,000 $8,094,000 $8,933,000
Long Term Debt And Capital Lease Obligation $7,568,000 $6,044,000 $6,620,000 $7,372,000
Current Debt And Capital Lease Obligation $1,771,000 $1,217,000 $1,474,000 $1,561,000
Liabilities
Total Liabilities Net Minority Interest $114,234,000 $109,458,000 $39,714,000 $36,219,000
Total Non Current Liabilities Net Minority Interest $11,292,000 $7,463,000 $6,620,000 $7,372,000
Other Non Current Liabilities $3,724,000 $1,419,000 - -
Current Liabilities $102,942,000 $101,995,000 $33,094,000 $28,847,000
Other Current Liabilities $3,579,000 $2,403,000 $2,199,000 $267,000
Payables And Accrued Expenses $97,592,000 $98,375,000 $29,421,000 $27,019,000
Payables $14,157,000 $9,273,000 $6,092,000 $4,024,000
Total Tax Payable $10,919,000 $4,288,000 $1,960,000 $43,000
Accounts Payable $3,238,000 $4,985,000 $4,132,000 $3,981,000
Equity
Common Stock Equity $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Total Equity Gross Minority Interest $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Stockholders Equity $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Gains Losses Not Affecting Retained Earnings $1,136,000 $-190,000 $638,000 $-728,000
Other Equity Adjustments $1,136,000 $-190,000 $638,000 $-728,000
Retained Earnings $24,163,000 $-180,668,000 $-269,827,000 $-280,759,000
Other
Ordinary Shares Number $29,192,000 $28,794,000 $28,236,673 $25,763,743
Share Issued $29,192,000 $28,794,000 $28,236,673 $25,763,743
Tangible Book Value $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Invested Capital $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Working Capital $921,660,000 $640,050,000 $554,815,000 $354,932,000
Capital Lease Obligations $9,339,000 $7,261,000 $8,094,000 $8,933,000
Total Capitalization $1,219,560,000 $946,380,000 $778,641,000 $522,231,000
Additional Paid In Capital $1,194,261,000 $1,127,238,000 $1,047,830,000 $803,718,000
Capital Stock $0 $0 $0 $0
Common Stock $0 $0 $0 $0
Long Term Capital Lease Obligation $7,568,000 $6,044,000 $6,620,000 $7,372,000
Current Capital Lease Obligation $1,771,000 $1,217,000 $1,474,000 $1,561,000
Current Accrued Expenses $83,435,000 $89,102,000 $23,329,000 $22,995,000
Investments And Advances $128,066,000 $152,114,000 $61,954,000 $4,621,000
Available For Sale Securities $128,066,000 $152,114,000 $61,954,000 $4,621,000
Net PPE $158,015,000 $161,448,000 $168,229,000 $169,726,000
Accumulated Depreciation $-31,281,000 $-21,919,000 $-12,827,000 $-6,793,000
Gross PPE $189,296,000 $183,367,000 $181,056,000 $176,519,000
Leases $27,227,000 $25,673,000 $25,068,000 $24,217,000
Construction In Progress $8,108,000 $5,778,000 $7,291,000 $131,331,000
Other Properties $40,008,000 $36,624,000 $34,271,000 $19,914,000
Machinery Furniture Equipment $4,711,000 $3,848,000 $3,246,000 $1,057,000
Buildings And Improvements $109,242,000 $111,444,000 $111,180,000 $0
Properties $0 $0 $0 $0
Finished Goods $9,313,000 $2,126,000 $627,000 $0
Work In Process $15,224,000 $10,743,000 $3,204,000 $0
Raw Materials $15,938,000 $13,639,000 $3,154,000 $0
Other Short Term Investments $331,487,000 $252,652,000 $173,850,000 $217,271,000
Other Investments - - - $4,621,000
Preferred Stock - - - -
Fetched: 2026-06-18
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $188,914,000 $119,182,000 $-100,603,000 $-153,548,000
Operating Activities
Operating Cash Flow $200,865,000 $123,420,000 $-88,804,000 $-100,569,000
Cash Flow From Continuing Operating Activities $200,865,000 $123,420,000 $-88,804,000 $-100,569,000
Operating Gains Losses $-5,953,000 $-6,069,000 $-105,092,000 $-570,000
Investing Activities
Capital Expenditure $-11,951,000 $-4,238,000 $-11,799,000 $-52,979,000
Investing Cash Flow $-58,417,000 $-163,439,000 $82,638,000 $-114,083,000
Cash Flow From Continuing Investing Activities $-58,417,000 $-163,439,000 $82,638,000 $-114,083,000
Net Other Investing Changes $435,000 - $100,000,000 -
Financing Activities
Issuance Of Capital Stock $0 $0 $159,726,000 $28,988,000
Financing Cash Flow $8,705,000 $27,014,000 $202,750,000 $35,347,000
Cash Flow From Continuing Financing Activities $8,705,000 $27,014,000 $202,750,000 $35,347,000
Net Other Financing Charges $-13,956,000 $-5,386,000 $-749,000 $-649,000
Net Common Stock Issuance $0 $0 $159,726,000 $28,988,000
Common Stock Issuance $0 $0 $159,726,000 $28,988,000
Other
Income Tax Paid Supplemental Data $15,673,000 $5,665,000 $0 $0
End Cash Position $496,304,000 $344,865,000 $358,328,000 $161,900,000
Beginning Cash Position $344,865,000 $358,328,000 $161,900,000 $341,246,000
Effect Of Exchange Rate Changes $286,000 $-458,000 $-156,000 $-41,000
Changes In Cash $151,153,000 $-13,005,000 $196,584,000 $-179,305,000
Proceeds From Stock Option Exercised $22,661,000 $32,400,000 $43,773,000 $7,008,000
Net Investment Purchase And Sale $-46,901,000 $-159,201,000 $-5,563,000 $-61,104,000
Sale Of Investment $375,639,000 $298,539,000 $503,213,000 $257,677,000
Purchase Of Investment $-422,540,000 $-457,740,000 $-508,776,000 $-318,781,000
Net PPE Purchase And Sale $-11,951,000 $-4,238,000 $-11,799,000 $-52,979,000
Purchase Of PPE $-11,951,000 $-4,238,000 $-11,799,000 $-52,979,000
Change In Working Capital $-36,419,000 $-14,457,000 $-38,522,000 $2,657,000
Change In Other Current Liabilities $1,702,000 $586,000 $-829,000 $-647,000
Change In Payables And Accrued Expense $4,948,000 $68,479,000 $10,434,000 $3,919,000
Change In Accrued Expense $4,122,000 $67,468,000 $10,535,000 $5,173,000
Change In Payable $826,000 $1,011,000 $-101,000 $-1,254,000
Change In Account Payable $826,000 $1,011,000 $-101,000 $-1,254,000
Change In Prepaid Assets $-14,659,000 $-8,909,000 $-1,612,000 $-615,000
Change In Inventory $-6,286,000 $-11,907,000 $-4,475,000 $0
Change In Receivables $-22,124,000 $-62,706,000 $-42,040,000 $0
Changes In Account Receivables $-22,124,000 $-62,706,000 $-42,040,000 $0
Other Non Cash Items $684,000 $652,000 $217,000 $34,000
Stock Based Compensation $54,514,000 $49,127,000 $39,933,000 $33,230,000
Amortization Of Securities $-498,000 $-1,706,000 $-2,183,000 $670,000
Deferred Tax $-22,845,000 $0 $0 -
Deferred Income Tax $-22,845,000 $0 $0 -
Depreciation Amortization Depletion $6,551,000 $6,714,000 $5,911,000 $3,385,000
Depreciation And Amortization $6,551,000 $6,714,000 $5,911,000 $3,385,000
Depreciation $6,551,000 $6,714,000 $5,911,000 $3,385,000
Gain Loss On Investment Securities $-5,953,000 $-6,069,000 $-5,092,000 $-570,000
Net Income From Continuing Operations $204,831,000 $89,159,000 $10,932,000 $-139,975,000
Change In Other Current Assets - - $-64,000 $-150,000
Unrealized Gain Loss On Investment Securities - - $-5,092,000 $-570,000
Gain Loss On Sale Of PPE - - $27,000 $72,000
Fetched: 2026-06-18