LYEL
Lyell Immunopharma, Inc.
Price Chart
Latest Quote
$13.00
| Previous Close | $12.63 |
| Open | $12.65 |
| Day High | $13.25 |
| Day Low | $12.35 |
| Volume | 132,420 |
Stock Information
| Shares Outstanding | 23.33M |
| Total Debt | $48.85M |
| Cash Equivalents | $254.02M |
| Revenue | $31K |
| Net Income | $-246.41M |
| Sector | Healthcare |
| Industry | Biotechnology |
| Market Cap | $303.34M |
| EPS (TTM) | $-13.62 |
| Exchange | NMS |
đ Comprehensive Analysis
Company Data
| Enterprise Value | $97.94M |
| Sales | $31K |
| Income | $-246.41M |
| Book/sh | $11.73 |
| Cash/sh | $10.89 |
| Employees | 161 |
Financial Ratios
| Quick Ratio | 6.88 |
| Current Ratio | 7.24 |
| Debt/Eq | 17.85 |
Returns & Margins
| ROA | -29.87% |
| ROE | -80.76% |
| Gross Margin | 100.00% |
| Operating Margin | -2213050.00% |
Ownership
| Insider Ownership | 39.84% |
| Institutional Ownership | 58.33% |
| Insider & Institutional transactions data not available | |
Valuation Ratios
| Forward P/E | -15.48 |
| P/S | 9785.26 |
| P/B | 1.11 |
Analyst Data
| Recommendation | buy |
| Target Price | $37.17 |
Technical Indicators
| SMA20 | $13.74 |
| SMA50 | $17.84 |
| SMA200 | $20.78 |
| RSI | 53.17 |
| ATR | 1.0568 |
| Shares Float | 6.49M |
| Short Float | 6.83% |
| Short Ratio | 19.69 |
| Volatility | -0.09 |
| Rel Volume | 0.91 |
Performance History
| Week | +4.50% |
| Month | -25.54% |
| Quarter | -34.01% |
| 6 Months | -61.00% |
| YTD | -55.14% |
| Year | +44.61% |
| 3 Years | -79.62% |
| 10 Years | -96.15% |
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Recent Price History
| Date | Close | Volume |
|---|---|---|
| 2026-06-24 | $13.00 | 132,900 |
| 2026-06-23 | $12.63 | 152,500 |
| 2026-06-22 | $11.97 | 184,600 |
| 2026-06-18 | $12.74 | 360,100 |
| 2026-06-17 | $12.52 | 167,100 |
| 2026-06-16 | $12.44 | 198,600 |
| 2026-06-15 | $13.55 | 82,700 |
| 2026-06-12 | $13.50 | 99,900 |
| 2026-06-11 | $13.72 | 142,500 |
| 2026-06-10 | $13.22 | 146,400 |
| 2026-06-09 | $12.70 | 99,200 |
| 2026-06-08 | $12.31 | 124,800 |
| 2026-06-05 | $11.97 | 96,700 |
| 2026-06-04 | $13.05 | 127,400 |
| 2026-06-03 | $12.57 | 413,000 |
| 2026-06-02 | $14.89 | 117,900 |
| 2026-06-01 | $17.15 | 82,600 |
| 2026-05-29 | $17.33 | 65,600 |
| 2026-05-28 | $16.83 | 57,200 |
| 2026-05-27 | $16.73 | 84,000 |
| 2026-05-26 | $16.37 | 134,000 |
About Lyell Immunopharma, Inc.
Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The company's lead product candidate include rondecabtagene autoleucel, an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development, which is in pivotal PiNACLE trial in the 3L+ setting and in a Phase 1/2 clinical trial in the 2L setting, as well as a second pivotal trial, PiNACLE-H2H, which is a Phase 3 head-to-head CAR T cell therapy randomized controlled trial of ronde-cel for LBCL in the 2L setting for the treatment of large B-cell lymphoma; and LYL273, a GCC-targeted CAR T-cell product candidate enhanced with CD19 CAR expression and controlled cytokine release designed to improve CAR T-cell expansion, immune cell infiltration, and cancer cell killing in the hostile solid tumor microenvironment, which is in Phase 1 clinical trial for the treatment of refractory metastatic colorectal cancer. The company develops therapies using various approaches, such as c-Jun overexpression and NR4A3 gene knockout, to endow functional resistance to exhaustion; Epi-R to generate population of stem-like T cells with reduced exhaustion and improved proliferation and antitumor activity; and CD62L positive enrichment to generate CAR T cells with enhanced antitumor activity. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.
đ° Latest News
Is Lyell Immunopharma (NASDAQ:LYEL) In A Good Position To Deliver On Growth Plans?
Simply Wall St. âĸ 2026-06-09T10:49:59ZLyell Immunopharma's Cancer Therapy Shows Improved Safety in Phase 1 Study
MT Newswires âĸ 2026-06-08T10:46:44ZLyell Immunopharma (LYEL) Loses 39.7% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner
Zacks âĸ 2026-06-04T13:35:03ZLyell Immunopharma Targets 2027 FDA Filing as CAR-T Pipeline Advances
MarketBeat âĸ 2026-05-27T08:03:20ZDown 33.7% in 4 Weeks, Here's Why You Should You Buy the Dip in Lyell Immunopharma (LYEL)
Zacks âĸ 2026-05-19T13:35:02ZLyell Immunopharma: Q4 Earnings Snapshot
Associated Press Finance âĸ 2026-03-12T22:10:19ZLyell starts first-of-its-kind CAR-T trial; New coalition aims to boost European biotechs
BioPharma Dive âĸ 2026-02-13T11:00:00ZThe Zacks Analyst Blog Mineralys, Lyell, Insmed and Nektar
Zacks âĸ 2025-12-26T07:33:00Z4 Drug, Biotech Stocks Rising More Than 50% in 2025 With Room to Grow
Zacks âĸ 2025-12-24T15:51:00ZInstitutional investors are Lyell Immunopharma, Inc.'s (NASDAQ:LYEL) biggest bettors and were rewarded after last week's US$72m market cap gain
Simply Wall St. âĸ 2025-12-17T15:37:40ZIncome Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Revenue | ||||
| Total Revenue | $36,000 | $61,000 | $130,000 | $84,683,000 |
| Operating Revenue | $36,000 | $61,000 | $130,000 | $84,683,000 |
| Expenses | ||||
| Total Expenses | $201,665,000 | $220,335,000 | $247,138,000 | $271,741,000 |
| Other Income Expense | $-85,899,000 | $-146,788,000 | $-11,077,000 | $-3,113,000 |
| Other Non Operating Income Expenses | $-18,124,000 | $4,694,000 | $1,846,000 | $1,887,000 |
| Net Non Operating Interest Income Expense | $13,080,000 | $24,068,000 | $23,453,000 | $7,053,000 |
| Operating Expense | $201,665,000 | $220,335,000 | $247,138,000 | $271,741,000 |
| Other Operating Expenses | $-2,145,000 | $-3,309,000 | $-2,790,000 | $-4,754,000 |
| General And Administrative Expense | $45,135,000 | $52,041,000 | $66,983,000 | $117,307,000 |
| Income & Earnings | ||||
| Net Income From Continuing Operation Net Minority Interest | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Net Interest Income | $13,080,000 | $24,068,000 | $23,453,000 | $7,053,000 |
| Interest Income | $13,080,000 | $24,068,000 | $23,453,000 | $7,053,000 |
| Normalized Income | $-206,673,000 | $-191,512,000 | $-221,709,000 | $-178,118,000 |
| Net Income From Continuing And Discontinued Operation | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Total Operating Income As Reported | $-269,404,000 | $-358,755,000 | $-247,008,000 | $-187,058,000 |
| Net Income Common Stockholders | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Net Income | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Net Income Including Noncontrolling Interests | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Net Income Continuous Operations | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Pretax Income | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Special Income Charges | $-67,775,000 | $-151,482,000 | $-12,923,000 | $-5,000,000 |
| Interest Income Non Operating | $13,080,000 | $24,068,000 | $23,453,000 | $7,053,000 |
| Operating Income | $-201,629,000 | $-220,274,000 | $-247,008,000 | $-187,058,000 |
| Per Share | ||||
| Diluted EPS | $-12.91 | $-23.26 | $-18.70 | $-14.80 |
| Basic EPS | $-12.91 | $-23.26 | $-18.70 | $-14.80 |
| Other | ||||
| Tax Effect Of Unusual Items | $0 | $0 | $0 | $0 |
| Tax Rate For Calcs | $0 | $0 | $0 | $0 |
| Normalized EBITDA (Bullshit earnings) | $-122,315,000 | $-49,161,000 | $-213,835,000 | $-164,038,000 |
| Total Unusual Items | $-67,775,000 | $-151,482,000 | $-12,923,000 | $-5,000,000 |
| Total Unusual Items Excluding Goodwill | $-67,775,000 | $-151,482,000 | $-12,923,000 | $-5,000,000 |
| Reconciled Depreciation | $11,539,000 | $19,631,000 | $20,250,000 | $18,020,000 |
| EBITDA (Bullshit earnings) | $-190,090,000 | $-200,643,000 | $-226,758,000 | $-169,038,000 |
| EBIT | $-201,629,000 | $-220,274,000 | $-247,008,000 | $-187,058,000 |
| Diluted Average Shares | $21,251,353 | $14,743,777 | $12,549,000 | $12,354,000 |
| Basic Average Shares | $21,251,353 | $14,743,777 | $12,549,000 | $12,354,000 |
| Diluted NI Availto Com Stockholders | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Other Special Charges | $66,332,000 | $87,184,000 | - | - |
| Write Off | $0 | $13,001,000 | $12,923,000 | $5,000,000 |
| Impairment Of Capital Assets | $1,443,000 | $51,297,000 | $0 | $0 |
| Research And Development | $158,675,000 | $171,603,000 | $182,945,000 | $159,188,000 |
| Selling General And Administration | $45,135,000 | $52,041,000 | $66,983,000 | $117,307,000 |
| Other Gand A | $45,135,000 | $52,041,000 | $66,983,000 | $117,307,000 |
| Restructuring And Mergern Acquisition | - | $87,184,000 | $0 | $0 |
Balance Sheet (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Assets | ||||
| Net Tangible Assets | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Total Assets | $340,052,000 | $490,859,000 | $750,029,000 | $937,561,000 |
| Total Non Current Assets | $79,113,000 | $111,265,000 | $195,343,000 | $286,266,000 |
| Other Non Current Assets | $6,471,000 | $6,312,000 | $4,519,000 | $4,960,000 |
| Investmentin Financial Assets | $0 | $13,014,000 | $16,506,000 | $70,117,000 |
| Current Assets | $260,939,000 | $379,594,000 | $554,686,000 | $651,295,000 |
| Other Current Assets | $13,719,000 | $9,067,000 | $8,463,000 | $11,143,000 |
| Cash Cash Equivalents And Short Term Investments | $247,220,000 | $370,527,000 | $546,223,000 | $640,152,000 |
| Cash And Cash Equivalents | $60,181,000 | $105,597,000 | $145,647,000 | $123,554,000 |
| Prepaid Assets | - | - | - | - |
| Debt | ||||
| Total Debt | $50,994,000 | $58,968,000 | $63,167,000 | $67,702,000 |
| Long Term Debt And Capital Lease Obligation | $41,921,000 | $50,994,000 | $56,894,000 | $63,168,000 |
| Current Debt And Capital Lease Obligation | $9,073,000 | $7,974,000 | $6,273,000 | $4,534,000 |
| Liabilities | ||||
| Total Liabilities Net Minority Interest | $91,850,000 | $108,035,000 | $95,077,000 | $104,309,000 |
| Total Non Current Liabilities Net Minority Interest | $42,438,000 | $54,247,000 | $60,558,000 | $67,281,000 |
| Other Non Current Liabilities | $517,000 | $3,253,000 | $3,664,000 | $4,113,000 |
| Current Liabilities | $49,412,000 | $53,788,000 | $34,519,000 | $37,028,000 |
| Other Current Liabilities | $2,559,000 | $2,999,000 | $3,069,000 | $6,708,000 |
| Current Deferred Liabilities | $2,535,000 | $483,000 | - | $0 |
| Payables And Accrued Expenses | $24,091,000 | $23,097,000 | $10,543,000 | $10,339,000 |
| Payables | $2,893,000 | $12,966,000 | $4,817,000 | $3,917,000 |
| Accounts Payable | $2,893,000 | $5,366,000 | $4,817,000 | $3,917,000 |
| Other Payable | - | $7,600,000 | - | - |
| Non Current Deferred Liabilities | - | - | - | $0 |
| Equity | ||||
| Common Stock Equity | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Total Equity Gross Minority Interest | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Stockholders Equity | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Gains Losses Not Affecting Retained Earnings | $242,000 | $291,000 | $-94,000 | $-7,599,000 |
| Other Equity Adjustments | $242,000 | $291,000 | $-94,000 | $-7,599,000 |
| Retained Earnings | $-1,619,554,000 | $-1,345,106,000 | $-1,002,112,000 | $-767,480,000 |
| Other | ||||
| Ordinary Shares Number | $21,251,353 | $14,743,777 | $12,697,885 | $12,478,350 |
| Share Issued | $21,251,353 | $14,743,777 | $12,697,885 | $12,478,350 |
| Tangible Book Value | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Invested Capital | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Working Capital | $211,527,000 | $325,806,000 | $520,167,000 | $614,267,000 |
| Capital Lease Obligations | $50,994,000 | $58,968,000 | $63,167,000 | $67,702,000 |
| Total Capitalization | $248,202,000 | $382,824,000 | $654,952,000 | $833,252,000 |
| Additional Paid In Capital | $1,867,512,000 | $1,727,638,000 | $1,657,133,000 | $1,608,306,000 |
| Capital Stock | $2,000 | $1,000 | $25,000 | $25,000 |
| Common Stock | $2,000 | $1,000 | $25,000 | $25,000 |
| Preferred Stock | $0 | $0 | $0 | $0 |
| Long Term Capital Lease Obligation | $41,921,000 | $50,994,000 | $56,894,000 | $63,168,000 |
| Current Deferred Revenue | $2,535,000 | $483,000 | - | $0 |
| Current Capital Lease Obligation | $9,073,000 | $7,974,000 | $6,273,000 | $4,534,000 |
| Pensionand Other Post Retirement Benefit Plans Current | $11,154,000 | $19,235,000 | $14,634,000 | $15,447,000 |
| Current Accrued Expenses | $21,198,000 | $10,131,000 | $5,726,000 | $6,422,000 |
| Investments And Advances | $19,000,000 | $32,014,000 | $48,507,000 | $115,041,000 |
| Other Investments | $19,000,000 | $19,000,000 | $32,001,000 | $44,924,000 |
| Net PPE | $53,642,000 | $72,939,000 | $142,317,000 | $166,265,000 |
| Accumulated Depreciation | $-74,278,000 | $-70,679,000 | $-51,647,000 | $-32,384,000 |
| Gross PPE | $127,920,000 | $143,618,000 | $193,964,000 | $198,649,000 |
| Leases | $79,739,000 | $79,613,000 | $118,319,000 | $116,930,000 |
| Construction In Progress | $452,000 | $241,000 | $128,000 | $4,148,000 |
| Other Properties | $45,243,000 | $60,845,000 | $73,031,000 | $75,224,000 |
| Machinery Furniture Equipment | $2,486,000 | $2,919,000 | $2,486,000 | $2,347,000 |
| Properties | $0 | $0 | $0 | $0 |
| Other Short Term Investments | $187,039,000 | $264,930,000 | $400,576,000 | $516,598,000 |
| Available For Sale Securities | - | $13,014,000 | $16,506,000 | $70,117,000 |
| Treasury Shares Number | - | - | $0 | - |
| Non Current Deferred Revenue | - | - | - | $0 |
Cash Flow Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Free Cash Flow | ||||
| Free Cash Flow | $-150,804,000 | $-162,858,000 | $-166,380,000 | $-193,831,000 |
| Operating Activities | ||||
| Operating Cash Flow | $-150,024,000 | $-162,394,000 | $-163,694,000 | $-169,555,000 |
| Cash Flow From Continuing Operating Activities | $-150,024,000 | $-162,394,000 | $-163,694,000 | $-169,555,000 |
| Operating Gains Losses | $22,559,000 | $1,311,000 | $1,509,000 | $-1,753,000 |
| Investing Activities | ||||
| Capital Expenditure | $-780,000 | $-464,000 | $-2,686,000 | $-24,276,000 |
| Investing Cash Flow | $54,097,000 | $122,424,000 | $184,048,000 | $-11,540,000 |
| Cash Flow From Continuing Investing Activities | $54,097,000 | $122,424,000 | $184,048,000 | $-11,540,000 |
| Net Other Investing Changes | $-41,195,000 | $-31,346,000 | - | - |
| Financing Activities | ||||
| Issuance Of Capital Stock | $50,000,000 | $0 | $0 | $0 |
| Financing Cash Flow | $50,406,000 | $1,326,000 | $1,743,000 | $10,635,000 |
| Cash Flow From Continuing Financing Activities | $50,406,000 | $1,326,000 | $1,743,000 | $10,635,000 |
| Net Other Financing Charges | $-1,000 | $-76,000 | $-457,000 | $-461,000 |
| Net Common Stock Issuance | $50,000,000 | $0 | $0 | $0 |
| Common Stock Issuance | $50,000,000 | $0 | $0 | $0 |
| Repurchase Of Capital Stock | - | - | - | $0 |
| Net Preferred Stock Issuance | - | - | - | $0 |
| Preferred Stock Issuance | - | - | - | $0 |
| Other | ||||
| End Cash Position | $61,766,000 | $107,287,000 | $145,931,000 | $123,834,000 |
| Beginning Cash Position | $107,287,000 | $145,931,000 | $123,834,000 | $294,294,000 |
| Changes In Cash | $-45,521,000 | $-38,644,000 | $22,097,000 | $-170,460,000 |
| Proceeds From Stock Option Exercised | $407,000 | $1,402,000 | $2,200,000 | $11,096,000 |
| Net Investment Purchase And Sale | $95,785,000 | $154,234,000 | $186,734,000 | $12,736,000 |
| Sale Of Investment | $374,684,000 | $548,941,000 | $663,614,000 | $419,052,000 |
| Purchase Of Investment | $-278,899,000 | $-394,707,000 | $-476,880,000 | $-406,316,000 |
| Net PPE Purchase And Sale | $-493,000 | $-464,000 | $-2,686,000 | $-24,276,000 |
| Sale Of PPE | $287,000 | $0 | $0 | - |
| Purchase Of PPE | $-780,000 | $-464,000 | $-2,686,000 | $-24,276,000 |
| Change In Working Capital | $-9,894,000 | $-3,120,000 | $3,421,000 | $-82,015,000 |
| Change In Other Current Liabilities | $-2,736,000 | $-411,000 | $-449,000 | $4,402,000 |
| Change In Payables And Accrued Expense | $-9,981,000 | $-4,484,000 | $745,000 | $204,000 |
| Change In Accrued Expense | $-7,642,000 | $-1,250,000 | $-719,000 | $-463,000 |
| Change In Payable | $-2,339,000 | $-3,234,000 | $1,464,000 | $667,000 |
| Change In Account Payable | $-2,339,000 | $-3,234,000 | $1,464,000 | $667,000 |
| Change In Prepaid Assets | $2,823,000 | $1,775,000 | $3,125,000 | $-1,968,000 |
| Other Non Cash Items | $61,907,000 | $80,017,000 | $-4,653,000 | $-6,683,000 |
| Stock Based Compensation | $41,829,000 | $33,144,000 | $47,084,000 | $81,924,000 |
| Asset Impairment Charge | $1,443,000 | $64,298,000 | $12,923,000 | $5,000,000 |
| Amortization Of Securities | $-4,959,000 | $-14,681,000 | $-9,596,000 | $-930,000 |
| Depreciation Amortization Depletion | $11,539,000 | $19,631,000 | $20,250,000 | $18,020,000 |
| Depreciation And Amortization | $11,539,000 | $19,631,000 | $20,250,000 | $18,020,000 |
| Gain Loss On Investment Securities | $19,215,000 | $-30,000 | - | $-1,856,000 |
| Gain Loss On Sale Of PPE | $3,344,000 | $1,341,000 | $1,509,000 | $103,000 |
| Net Income From Continuing Operations | $-274,448,000 | $-342,994,000 | $-234,632,000 | $-183,118,000 |
| Preferred Stock Payments | - | - | - | $0 |
| Common Stock Payments | - | - | - | $0 |
| Change In Other Working Capital | - | - | - | $-84,653,000 |
| Net Investment Properties Purchase And Sale | - | - | - | - |
| Purchase Of Investment Properties | - | - | - | - |