PALI
Palisade Bio, Inc.
Price Chart
Latest Quote
$1.84
| Previous Close | $1.87 |
| Open | $1.90 |
| Day High | $1.97 |
| Day Low | $1.82 |
| Volume | 1,940,088 |
Stock Information
| Shares Outstanding | 173.58M |
| Cash Equivalents | $132.63M |
| Net Income | $-24.15M |
| Sector | Healthcare |
| Industry | Biotechnology |
| Market Cap | $319.75M |
| P/E Ratio | 15.33 |
| EPS (TTM) | $0.12 |
| Exchange | NCM |
đ Comprehensive Analysis
Company Data
| Enterprise Value | $186.76M |
| Income | $-24.15M |
| Book/sh | $0.76 |
| Cash/sh | $0.76 |
| Employees | 14 |
Financial Ratios
| Quick Ratio | 23.60 |
| Current Ratio | 23.71 |
Returns & Margins
| ROA | -23.40% |
| ROE | -36.40% |
Ownership
| Insider Ownership | 1.64% |
| Institutional Ownership | 93.85% |
| Insider & Institutional transactions data not available | |
Valuation Ratios
| Forward P/E | -7.83 |
| P/B | 2.42 |
Analyst Data
| Recommendation | none |
| Target Price | $9.71 |
Technical Indicators
| SMA20 | $1.86 |
| SMA50 | $1.97 |
| SMA200 | $1.78 |
| RSI | 37.76 |
| ATR | 0.1479 |
| Shares Float | 132.08M |
| Short Float | 17.75% |
| Short Ratio | 11.56 |
| Volatility | 1.53 |
| Rel Volume | 0.78 |
Performance History
| Week | +7.60% |
| Month | -2.13% |
| Quarter | -2.65% |
| 6 Months | +9.52% |
| YTD | -26.40% |
| Year | +187.50% |
| 3 Years | -92.43% |
| 5 Years | -99.94% |
| 10 Years | -100.00% |
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Recent Price History
| Date | Close | Volume |
|---|---|---|
| 2026-06-22 | $1.84 | 2,088,100 |
| 2026-06-18 | $1.87 | 4,040,400 |
| 2026-06-17 | $1.76 | 3,952,300 |
| 2026-06-16 | $1.78 | 3,491,900 |
| 2026-06-15 | $1.69 | 2,109,900 |
| 2026-06-12 | $1.71 | 2,181,700 |
| 2026-06-11 | $1.78 | 3,094,000 |
| 2026-06-10 | $1.68 | 1,359,800 |
| 2026-06-09 | $1.69 | 1,704,400 |
| 2026-06-08 | $1.74 | 1,100,800 |
| 2026-06-05 | $1.74 | 4,319,500 |
| 2026-06-04 | $1.93 | 1,526,600 |
| 2026-06-03 | $1.93 | 3,392,400 |
| 2026-06-02 | $1.86 | 5,199,200 |
| 2026-06-01 | $2.08 | 3,372,400 |
| 2026-05-29 | $2.12 | 751,900 |
| 2026-05-28 | $2.06 | 1,342,400 |
| 2026-05-27 | $2.07 | 2,954,000 |
| 2026-05-26 | $1.99 | 2,578,100 |
About Palisade Bio, Inc.
Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn's disease. The company has a research collaboration and license agreement with Giiant Pharma, Inc. for the development, manufacture, and commercialization of its compounds; license agreement with the Regents of the University of California for sole purpose of maintaining the Newsoara Co-Development; and a co-development and distribution agreement with Newsoara Biopharma Co., Ltd. The company was founded in 2001 and is headquartered in Denver, Colorado.
đ° Latest News
Why a $5 Million New Position Signals Confidence in This Epilepsy Drug Pipeline
Motley Fool âĸ 2026-05-21T21:51:11ZWhy This Fund Added $12 Million to a Biotech Stock That's Now Down 58% in a Year
Motley Fool âĸ 2026-05-21T21:39:19ZPalisade Bio (PALI) Reports Q1 2026 Results as R&D Expenses Rise to $6.4M
Insider Monkey âĸ 2026-05-18T04:49:51ZWe're Not Worried About Palisade Bio's (NASDAQ:PALI) Cash Burn
Simply Wall St. âĸ 2026-05-15T11:00:19ZWolfe Highlights Differentiation Potential in Palisade Bio, Inc. (PALI) Clinical Profile
Insider Monkey âĸ 2026-04-17T13:57:34ZTSX Penny Stocks To Watch In March 2026
Simply Wall St. âĸ 2026-03-31T19:05:32ZUpdate: Palisade Bio Shares Fall After Phase 1b Data on PALI-2108 in Fibrostenotic Crohn's Disease
MT Newswires âĸ 2026-03-31T18:50:04ZPalisade Bio Shares Phase 1b PALI-2108 Data Showing Safety, PK and Early Crohnâs Efficacy Signals
MarketBeat âĸ 2026-03-31T18:35:55ZStructure Therapeutics Slides 28% This Year as $6 Million Stake Emerges
Motley Fool âĸ 2026-03-22T20:26:16ZPalisade Bio (PALI) Reports Positive Phase 1b Data for PALI-2108 in UC Patients
Insider Monkey âĸ 2026-03-18T21:31:56ZIncome Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Revenue | ||||
| Total Revenue | $0 | $0 | $250,000 | $0 |
| Operating Revenue | $0 | $0 | $250,000 | $0 |
| Expenses | ||||
| Interest Expense | $10,000 | $12,000 | $15,000 | $13,000 |
| Total Expenses | $18,056,000 | $14,859,000 | $13,095,000 | $15,311,000 |
| Other Income Expense | $1,285,000 | $433,000 | $560,000 | $1,064,000 |
| Other Non Operating Income Expenses | $1,285,000 | $433,000 | $785,000 | $2,584,000 |
| Net Non Operating Interest Income Expense | $-10,000 | $-12,000 | $-15,000 | $-13,000 |
| Interest Expense Non Operating | $10,000 | $12,000 | $15,000 | $13,000 |
| Operating Expense | $18,056,000 | $14,859,000 | $13,095,000 | $15,311,000 |
| General And Administrative Expense | $7,864,000 | $5,796,000 | $6,202,000 | $8,764,000 |
| Total Other Finance Cost | - | - | - | - |
| Income & Earnings | ||||
| Net Income From Continuing Operation Net Minority Interest | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Net Interest Income | $-10,000 | $-12,000 | $-15,000 | $-13,000 |
| Normalized Income | $-16,781,000 | $-14,438,000 | $-12,075,000 | $-12,740,000 |
| Net Income From Continuing And Discontinued Operation | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Total Operating Income As Reported | $-18,056,000 | $-14,859,000 | $-13,070,000 | $-15,721,000 |
| Net Income Common Stockholders | $-16,781,000 | $-14,438,000 | $-12,316,000 | $-14,548,000 |
| Net Income | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Net Income Including Noncontrolling Interests | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Net Income Continuous Operations | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Pretax Income | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Operating Income | $-18,056,000 | $-14,859,000 | $-12,845,000 | $-15,311,000 |
| Special Income Charges | - | $0 | $-225,000 | $-410,000 |
| Average Dilution Earnings | - | - | - | $0 |
| Per Share | ||||
| Diluted EPS | $-0.30 | $-10.19 | $-27.01 | $-247.95 |
| Basic EPS | $-0.30 | $-10.19 | $-27.01 | $-247.95 |
| Other | ||||
| Tax Effect Of Unusual Items | $0 | $0 | $0 | $0 |
| Tax Rate For Calcs | $0 | $0 | $0 | $0 |
| Normalized EBITDA (Bullshit earnings) | $-16,768,000 | $-14,423,000 | $-12,056,000 | $-12,724,000 |
| Reconciled Depreciation | $3,000 | $3,000 | $4,000 | $3,000 |
| EBITDA (Bullshit earnings) | $-16,768,000 | $-14,423,000 | $-12,281,000 | $-14,244,000 |
| EBIT | $-16,771,000 | $-14,426,000 | $-12,285,000 | $-14,247,000 |
| Diluted Average Shares | $55,669,821 | $1,416,471 | $456,014 | $58,687 |
| Basic Average Shares | $55,669,821 | $1,416,471 | $456,014 | $58,687 |
| Diluted NI Availto Com Stockholders | $-16,781,000 | $-14,438,000 | $-12,316,000 | $-14,548,000 |
| Research And Development | $10,192,000 | $9,063,000 | $6,893,000 | $6,547,000 |
| Selling General And Administration | $7,864,000 | $5,796,000 | $6,202,000 | $8,764,000 |
| Other Gand A | $7,864,000 | $5,796,000 | $6,202,000 | $8,764,000 |
| Total Unusual Items | - | $0 | $-225,000 | $-1,520,000 |
| Total Unusual Items Excluding Goodwill | - | $0 | $-225,000 | $-1,520,000 |
| Otherunder Preferred Stock Dividend | - | $0 | $16,000 | $288,000 |
| Restructuring And Mergern Acquisition | - | $0 | $225,000 | $410,000 |
| Gain On Sale Of Security | - | - | - | $-1,110,000 |
| Other Special Charges | - | - | - | - |
Balance Sheet (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Assets | ||||
| Net Tangible Assets | $129,380,000 | $7,492,000 | $11,313,000 | $12,479,000 |
| Total Assets | $134,344,000 | $10,880,000 | $14,052,000 | $15,763,000 |
| Total Non Current Assets | $123,000 | $386,000 | $724,000 | $1,030,000 |
| Other Non Current Assets | $123,000 | $299,000 | $38,000 | $38,000 |
| Current Assets | $134,221,000 | $10,494,000 | $13,328,000 | $14,733,000 |
| Current Deferred Assets | $0 | $75,000 | $112,000 | $114,000 |
| Prepaid Assets | $572,000 | $574,000 | $636,000 | $798,000 |
| Receivables | $264,000 | $24,000 | $148,000 | $1,438,000 |
| Other Receivables | $264,000 | $24,000 | $148,000 | $1,438,000 |
| Cash Cash Equivalents And Short Term Investments | $133,385,000 | $9,821,000 | $12,432,000 | $12,383,000 |
| Cash And Cash Equivalents | $133,385,000 | $9,821,000 | $12,432,000 | $12,383,000 |
| Non Current Prepaid Assets | - | $273,000 | $478,000 | $682,000 |
| Non Current Deferred Assets | - | - | - | - |
| Accounts Receivable | - | - | - | - |
| Debt | ||||
| Total Debt | $71,000 | $169,000 | $369,000 | $404,000 |
| Current Debt And Capital Lease Obligation | $71,000 | $169,000 | $279,000 | $193,000 |
| Current Debt | $71,000 | $79,000 | $158,000 | $88,000 |
| Other Current Borrowings | $71,000 | $79,000 | $158,000 | $88,000 |
| Long Term Debt And Capital Lease Obligation | - | $0 | $90,000 | $211,000 |
| Liabilities | ||||
| Total Liabilities Net Minority Interest | $4,964,000 | $3,388,000 | $2,739,000 | $3,284,000 |
| Total Non Current Liabilities Net Minority Interest | $328,000 | $152,000 | $153,000 | $272,000 |
| Other Non Current Liabilities | $266,000 | $150,000 | $61,000 | $61,000 |
| Derivative Product Liabilities | $62,000 | $2,000 | $2,000 | $61,000 |
| Current Liabilities | $4,636,000 | $3,236,000 | $2,586,000 | $3,012,000 |
| Other Current Liabilities | $313,000 | - | - | - |
| Payables And Accrued Expenses | $2,954,000 | $2,345,000 | $1,398,000 | $2,153,000 |
| Payables | $930,000 | $1,214,000 | $844,000 | $1,828,000 |
| Accounts Payable | $930,000 | $1,214,000 | $844,000 | $1,828,000 |
| Equity | ||||
| Common Stock Equity | $129,378,000 | $7,490,000 | $11,311,000 | $12,477,000 |
| Preferred Stock Equity | $2,000 | $2,000 | $2,000 | $2,000 |
| Total Equity Gross Minority Interest | $129,380,000 | $7,492,000 | $11,313,000 | $12,479,000 |
| Stockholders Equity | $129,380,000 | $7,492,000 | $11,313,000 | $12,479,000 |
| Retained Earnings | $-152,725,000 | $-135,944,000 | $-121,506,000 | $-109,190,000 |
| Preferred Securities Outside Stock Equity | - | - | - | - |
| Other | ||||
| Ordinary Shares Number | $159,644,017 | $2,968,646 | $818,059 | $396,287 |
| Share Issued | $159,644,017 | $2,968,646 | $818,059 | $396,287 |
| Tangible Book Value | $129,378,000 | $7,490,000 | $11,311,000 | $12,477,000 |
| Invested Capital | $129,449,000 | $7,569,000 | $11,469,000 | $12,565,000 |
| Working Capital | $129,585,000 | $7,258,000 | $10,742,000 | $11,721,000 |
| Capital Lease Obligations | $0 | $90,000 | $211,000 | $316,000 |
| Total Capitalization | $129,380,000 | $7,492,000 | $11,313,000 | $12,479,000 |
| Additional Paid In Capital | $280,509,000 | $143,407,000 | $132,811,000 | $121,637,000 |
| Capital Stock | $1,596,000 | $29,000 | $8,000 | $32,000 |
| Common Stock | $1,594,000 | $27,000 | $6,000 | $30,000 |
| Preferred Stock | $2,000 | $2,000 | $2,000 | $2,000 |
| Current Capital Lease Obligation | $0 | $90,000 | $121,000 | $105,000 |
| Pensionand Other Post Retirement Benefit Plans Current | $1,298,000 | $722,000 | $909,000 | $666,000 |
| Current Accrued Expenses | $2,024,000 | $1,131,000 | $554,000 | $325,000 |
| Net PPE | $0 | $87,000 | $208,000 | $310,000 |
| Gross PPE | $0 | $87,000 | $208,000 | $310,000 |
| Buildings And Improvements | $0 | $84,000 | $198,000 | $300,000 |
| Properties | $0 | $0 | $0 | $0 |
| Long Term Capital Lease Obligation | - | $0 | $90,000 | $211,000 |
| Other Properties | - | $3,000 | $10,000 | $10,000 |
| Preferred Shares Number | - | - | $200,000 | $200,000 |
| Machinery Furniture Equipment | - | - | - | - |
Cash Flow Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Free Cash Flow | ||||
| Free Cash Flow | $-10,847,000 | $-12,193,000 | $-11,137,000 | $-13,370,000 |
| Operating Activities | ||||
| Operating Cash Flow | $-10,847,000 | $-12,193,000 | $-11,133,000 | $-13,360,000 |
| Cash Flow From Continuing Operating Activities | $-10,847,000 | $-12,193,000 | $-11,133,000 | $-13,360,000 |
| Operating Gains Losses | $349,000 | $-50,000 | $145,000 | $-1,316,000 |
| Investing Activities | ||||
| Investing Cash Flow | - | $0 | $-4,000 | $-10,000 |
| Cash Flow From Continuing Investing Activities | - | $0 | $-4,000 | $-10,000 |
| Capital Expenditure | - | - | $-4,000 | $-10,000 |
| Financing Activities | ||||
| Issuance Of Capital Stock | $128,219,000 | $8,435,000 | $9,419,000 | $14,401,000 |
| Financing Cash Flow | $134,440,000 | $9,582,000 | $11,186,000 | $15,258,000 |
| Cash Flow From Continuing Financing Activities | $134,440,000 | $9,582,000 | $11,186,000 | $15,258,000 |
| Net Other Financing Charges | $-1,113,000 | $-944,000 | $-617,000 | $-627,000 |
| Net Common Stock Issuance | $128,219,000 | $8,435,000 | $9,419,000 | $14,401,000 |
| Common Stock Issuance | $128,219,000 | $8,435,000 | $9,419,000 | $14,401,000 |
| Net Preferred Stock Issuance | - | - | - | $0 |
| Preferred Stock Issuance | - | - | - | $0 |
| Other | ||||
| Repayment Of Debt | $-320,000 | $-426,000 | $-391,000 | $-790,000 |
| Interest Paid Supplemental Data | $10,000 | $14,000 | $14,000 | $12,000 |
| End Cash Position | $133,440,000 | $9,847,000 | $12,458,000 | $12,409,000 |
| Beginning Cash Position | $9,847,000 | $12,458,000 | $12,409,000 | $10,521,000 |
| Changes In Cash | $123,593,000 | $-2,611,000 | $49,000 | $1,888,000 |
| Proceeds From Stock Option Exercised | $7,654,000 | $2,517,000 | $2,775,000 | $2,274,000 |
| Net Issuance Payments Of Debt | $-320,000 | $-426,000 | $-391,000 | $-790,000 |
| Net Short Term Debt Issuance | $-320,000 | $-426,000 | $-391,000 | $-790,000 |
| Short Term Debt Payments | $-320,000 | $-426,000 | $-391,000 | $-790,000 |
| Change In Working Capital | $1,639,000 | $1,391,000 | $400,000 | $1,250,000 |
| Change In Other Current Liabilities | $-90,000 | $-121,000 | $-105,000 | $-151,000 |
| Change In Payables And Accrued Expense | $1,200,000 | $762,000 | $-200,000 | $399,000 |
| Change In Accrued Expense | $576,000 | $-56,000 | $292,000 | - |
| Change In Payable | $624,000 | $818,000 | $-492,000 | - |
| Change In Account Payable | $624,000 | $818,000 | $-492,000 | - |
| Change In Prepaid Assets | $529,000 | $750,000 | $705,000 | $1,027,000 |
| Other Non Cash Items | $-87,000 | $249,000 | $-6,000 | $-69,000 |
| Stock Based Compensation | $3,955,000 | $652,000 | $624,000 | $1,032,000 |
| Asset Impairment Charge | $75,000 | $0 | - | - |
| Depreciation Amortization Depletion | $3,000 | $3,000 | $4,000 | $3,000 |
| Depreciation And Amortization | $3,000 | $3,000 | $4,000 | $3,000 |
| Depreciation | $3,000 | $3,000 | $4,000 | $3,000 |
| Gain Loss On Investment Securities | $349,000 | $-54,000 | $145,000 | $-1,316,000 |
| Gain Loss On Sale Of PPE | $0 | $4,000 | $0 | - |
| Net Income From Continuing Operations | $-16,781,000 | $-14,438,000 | $-12,300,000 | $-14,260,000 |
| Net PPE Purchase And Sale | - | $0 | $-4,000 | $-10,000 |
| Purchase Of PPE | - | $0 | $-4,000 | $-10,000 |
| Change In Other Working Capital | - | - | $292,000 | $-25,000 |
| Issuance Of Debt | - | - | - | $0 |
| Net Long Term Debt Issuance | - | - | - | $-790,000 |
| Long Term Debt Payments | - | - | - | $-790,000 |
| Long Term Debt Issuance | - | - | - | $0 |
| Net Business Purchase And Sale | - | - | - | $0 |
| Sale Of Business | - | - | - | $0 |
| Purchase Of Business | - | - | - | $0 |
| Change In Receivables | - | - | - | $0 |