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PRLD

Prelude Therapeutics Incorporated

Price Chart
Latest Quote

$4.32

-0.03 (-0.69%)
Current Price
Previous Close $4.35
Open $4.30
Day High $4.64
Day Low $4.16
Volume 1,076,626
Fetched: 2026-06-22T09:07:41
Stock Information
Shares Outstanding 64.92M
Total Debt $17.72M
Cash Equivalents $81.55M
Revenue $16.72M
Net Income $-77.80M
Sector Healthcare
Industry Biotechnology
Market Cap $344.07M
EPS (TTM) $-1.00
Exchange NMS
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📊 Comprehensive Analysis
Company Data
Enterprise Value$364.61M
Sales$16.72M
Income$-77.80M
Book/sh$0.73
Cash/sh$1.26
Employees79
Financial Ratios
Quick Ratio1.96
Current Ratio2.03
Debt/Eq29.45
Returns & Margins
ROA-39.69%
ROE-95.25%
Gross Margin100.00%
Operating Margin-309.54%
Ownership
Insider Ownership13.80%
Institutional Ownership64.54%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E-4.60
P/S20.58
P/B5.93
Analyst Data
Recommendationnone
Target Price$8.00
Technical Indicators
SMA20$4.06
SMA50$4.38
SMA200$2.65
RSI58.26
ATR0.3430
Shares Float27.59M
Short Float6.73%
Short Ratio3.84
Volatility1.01
Rel Volume3.25
Performance History
Week+5.11%
Month+1.17%
Quarter+35.42%
6 Months+117.09%
YTD+58.24%
Year+365.52%
3 Years-22.72%
5 Years-86.15%
10 Years-83.51%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-18 $4.32 1,076,600
2026-06-17 $4.35 317,600
2026-06-16 $4.20 450,500
2026-06-15 $4.46 327,400
2026-06-12 $4.49 314,300
2026-06-11 $4.11 204,900
2026-06-10 $3.95 192,700
2026-06-09 $3.94 235,400
2026-06-08 $3.84 281,300
2026-06-05 $3.81 220,900
2026-06-04 $4.08 399,900
2026-06-03 $3.66 375,800
2026-06-02 $3.50 385,000
2026-06-01 $3.82 237,800
2026-05-29 $3.92 288,200
2026-05-28 $3.93 373,200
2026-05-27 $4.16 170,900
2026-05-26 $4.09 311,100
2026-05-22 $4.27 241,600
2026-05-21 $4.33 220,600
2026-05-20 $4.50 386,100
2026-05-19 $4.27 404,300
About Prelude Therapeutics Incorporated

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.

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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Total Revenue $12,140,000 $7,000,000 $0 $0
Operating Revenue $12,140,000 $7,000,000 $0 $0
Expenses
Total Expenses $116,706,000 $146,714,000 $132,277,000 $123,540,000
Other Income Expense $5,068,000 $12,541,000 $10,445,000 $8,102,000
Other Non Operating Income Expenses $5,068,000 $12,541,000 $10,445,000 $8,102,000
Operating Expense $116,706,000 $146,714,000 $132,277,000 $123,540,000
General And Administrative Expense $22,406,000 $28,719,000 $28,884,000 $30,651,000
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Normalized Income $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Net Income From Continuing And Discontinued Operation $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Total Operating Income As Reported $-104,566,000 $-139,714,000 $-132,277,000 $-123,540,000
Net Income Common Stockholders $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Net Income $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Net Income Including Noncontrolling Interests $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Net Income Continuous Operations $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Pretax Income $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Operating Income $-104,566,000 $-139,714,000 $-132,277,000 $-123,540,000
Per Share
Diluted EPS $-1.29 $-1.68 $-2.02 $-2.44
Basic EPS $-1.29 $-1.68 $-2.02 $-2.44
Other
Tax Effect Of Unusual Items $0 $0 $0 $0
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $-102,855,000 $-137,942,000 $-131,108,000 $-122,216,000
Reconciled Depreciation $1,711,000 $1,772,000 $1,169,000 $1,324,000
EBITDA (Bullshit earnings) $-102,855,000 $-137,942,000 $-131,108,000 $-122,216,000
EBIT $-104,566,000 $-139,714,000 $-132,277,000 $-123,540,000
Diluted Average Shares $76,956,194 $75,805,840 $60,357,052 $47,371,589
Basic Average Shares $76,956,194 $75,805,840 $60,357,052 $47,371,589
Diluted NI Availto Com Stockholders $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Research And Development $94,300,000 $117,995,000 $103,393,000 $92,889,000
Selling General And Administration $22,406,000 $28,719,000 $28,884,000 $30,651,000
Other Gand A $22,406,000 $28,719,000 $28,884,000 $30,651,000
Fetched: 2026-06-20
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $68,637,000 $131,459,000 $237,090,000 $195,437,000
Total Assets $141,315,000 $175,515,000 $277,665,000 $220,500,000
Total Non Current Assets $35,623,000 $39,620,000 $42,076,000 $16,120,000
Other Non Current Assets $3,345,000 $4,154,000 $4,339,000 $9,420,000
Current Assets $105,692,000 $135,895,000 $235,589,000 $204,380,000
Other Current Assets $2,478,000 $2,281,000 $2,654,000 $2,652,000
Cash Cash Equivalents And Short Term Investments $103,214,000 $133,614,000 $232,935,000 $201,728,000
Cash And Cash Equivalents $35,256,000 $12,474,000 $25,291,000 $30,605,000
Prepaid Assets - - - -
Debt
Total Debt $17,789,000 $18,025,000 $16,888,000 $1,832,000
Long Term Debt And Capital Lease Obligation $15,045,000 $15,325,000 $15,407,000 $0
Current Debt And Capital Lease Obligation $2,744,000 $2,700,000 $1,481,000 $1,832,000
Liabilities
Total Liabilities Net Minority Interest $72,678,000 $44,056,000 $40,575,000 $25,063,000
Total Non Current Liabilities Net Minority Interest $19,684,000 $18,415,000 $18,746,000 $3,361,000
Other Non Current Liabilities $2,841,000 $3,090,000 $3,339,000 $3,361,000
Non Current Deferred Liabilities $1,798,000 $0 - -
Current Liabilities $52,994,000 $25,641,000 $21,829,000 $21,702,000
Other Current Liabilities $965,000 $771,000 $945,000 $524,000
Current Deferred Liabilities $33,734,000 $0 - -
Payables And Accrued Expenses $8,413,000 $13,148,000 $10,246,000 $13,664,000
Payables $3,983,000 $7,732,000 $4,580,000 $6,777,000
Accounts Payable $3,983,000 $7,732,000 $4,580,000 $6,777,000
Equity
Common Stock Equity $68,637,000 $131,459,000 $237,090,000 $195,437,000
Total Equity Gross Minority Interest $68,637,000 $131,459,000 $237,090,000 $195,437,000
Stockholders Equity $68,637,000 $131,459,000 $237,090,000 $195,437,000
Gains Losses Not Affecting Retained Earnings $8,000 $35,000 $223,000 $-1,692,000
Other Equity Adjustments $8,000 $35,000 $223,000 $-1,692,000
Retained Earnings $-683,061,000 $-583,563,000 $-456,390,000 $-334,558,000
Other
Ordinary Shares Number $62,953,628 $55,149,118 $54,914,254 $47,899,031
Share Issued $62,953,628 $55,149,118 $54,914,254 $47,899,031
Tangible Book Value $68,637,000 $131,459,000 $237,090,000 $195,437,000
Invested Capital $68,637,000 $131,459,000 $237,090,000 $195,437,000
Working Capital $52,698,000 $110,254,000 $213,760,000 $182,678,000
Capital Lease Obligations $17,789,000 $18,025,000 $16,888,000 $1,832,000
Total Capitalization $68,637,000 $131,459,000 $237,090,000 $195,437,000
Additional Paid In Capital $751,684,000 $714,982,000 $693,252,000 $531,682,000
Capital Stock $6,000 $5,000 $5,000 $5,000
Common Stock $6,000 $5,000 $5,000 $5,000
Non Current Deferred Revenue $1,798,000 $0 - -
Long Term Capital Lease Obligation $15,045,000 $15,325,000 $15,407,000 $0
Current Deferred Revenue $33,734,000 $0 - -
Current Capital Lease Obligation $2,744,000 $2,700,000 $1,481,000 $1,832,000
Pensionand Other Post Retirement Benefit Plans Current $7,138,000 $9,022,000 $9,157,000 $5,682,000
Current Accrued Expenses $4,430,000 $5,416,000 $5,666,000 $6,887,000
Net PPE $32,278,000 $35,466,000 $37,737,000 $6,700,000
Accumulated Depreciation $-6,929,000 $-5,258,000 $-3,566,000 $-3,319,000
Gross PPE $39,207,000 $40,724,000 $41,303,000 $10,019,000
Leases $1,706,000 $1,700,000 $1,582,000 $875,000
Other Properties $35,096,000 $36,619,000 $37,055,000 $7,420,000
Machinery Furniture Equipment $2,405,000 $2,405,000 $2,328,000 $87,000
Properties $0 $0 $0 $0
Other Short Term Investments $67,958,000 $121,140,000 $207,644,000 $171,123,000
Construction In Progress - $0 $338,000 $1,637,000
Treasury Shares Number - - $0 -
Fetched: 2026-06-20
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $-56,369,000 $-103,652,000 $-110,576,000 $-86,748,000
Operating Activities
Operating Cash Flow $-56,302,000 $-102,888,000 $-107,063,000 $-83,729,000
Cash Flow From Continuing Operating Activities $-56,302,000 $-102,888,000 $-107,063,000 $-83,729,000
Investing Activities
Capital Expenditure $-67,000 $-764,000 $-3,513,000 $-3,019,000
Investing Cash Flow $53,459,000 $90,191,000 $-34,646,000 $81,691,000
Cash Flow From Continuing Investing Activities $53,459,000 $90,191,000 $-34,646,000 $81,691,000
Financing Activities
Issuance Of Capital Stock $24,875,000 $0 $135,731,000 $0
Financing Cash Flow $24,816,000 $-120,000 $136,395,000 $815,000
Cash Flow From Continuing Financing Activities $24,816,000 $-120,000 $136,395,000 $815,000
Net Other Financing Charges $-17,000 $-164,000 $-17,000 -
Net Common Stock Issuance $24,875,000 $0 $135,731,000 $0
Common Stock Issuance $24,875,000 $0 $135,731,000 $0
Net Preferred Stock Issuance - - - -
Preferred Stock Issuance - - - -
Other
Repayment Of Debt $-208,000 $-395,000 $0 -
End Cash Position $38,491,000 $16,518,000 $29,335,000 $34,649,000
Beginning Cash Position $16,518,000 $29,335,000 $34,649,000 $35,872,000
Changes In Cash $21,973,000 $-12,817,000 $-5,314,000 $-1,223,000
Proceeds From Stock Option Exercised $166,000 $439,000 $681,000 $815,000
Net Issuance Payments Of Debt $-208,000 $-395,000 $0 -
Net Long Term Debt Issuance $-208,000 $-395,000 $0 -
Long Term Debt Payments $-208,000 $-395,000 $0 -
Net Investment Purchase And Sale $53,526,000 $90,955,000 $-31,133,000 $84,710,000
Sale Of Investment $154,392,000 $143,649,000 $190,500,000 $203,933,000
Purchase Of Investment $-100,866,000 $-52,694,000 $-221,633,000 $-119,223,000
Net PPE Purchase And Sale $-67,000 $-764,000 $-3,513,000 $-3,019,000
Purchase Of PPE $-67,000 $-764,000 $-3,513,000 $-3,019,000
Change In Working Capital $28,409,000 $4,216,000 $-10,479,000 $932,000
Change In Other Working Capital $35,532,000 - - -
Change In Other Current Liabilities $-28,000 $1,051,000 $-1,624,000 $-1,711,000
Change In Payables And Accrued Expense $-6,898,000 $2,497,000 $252,000 $6,486,000
Change In Accrued Expense $-2,980,000 $-808,000 $2,522,000 $6,833,000
Change In Payable $-3,918,000 $3,305,000 $-2,270,000 $-347,000
Change In Account Payable $-3,918,000 $3,305,000 $-2,270,000 $-347,000
Change In Prepaid Assets $-197,000 $668,000 $-9,107,000 $-3,843,000
Other Non Cash Items $1,534,000 $1,591,000 $1,936,000 $1,718,000
Stock Based Compensation $11,913,000 $21,345,000 $25,616,000 $25,144,000
Amortization Of Securities $-371,000 $-4,639,000 $-3,473,000 $2,591,000
Depreciation Amortization Depletion $1,711,000 $1,772,000 $1,169,000 $1,324,000
Depreciation And Amortization $1,711,000 $1,772,000 $1,169,000 $1,324,000
Net Income From Continuing Operations $-99,498,000 $-127,173,000 $-121,832,000 $-115,438,000
Gain Loss On Sale Of PPE - - - -
Fetched: 2026-06-20