SNTI
Senti Biosciences Holdings, Inc.
Price Chart
Latest Quote
$0.93
| Previous Close | $0.95 |
| Open | $0.93 |
| Day High | $0.97 |
| Day Low | $0.92 |
| Volume | 113,870 |
Stock Information
| Shares Outstanding | 31.14M |
| Total Debt | $28.89M |
| Cash Equivalents | $16.73M |
| Revenue | $38K |
| Net Income | $-51.55M |
| Sector | Healthcare |
| Industry | Biotechnology |
| Market Cap | $29.02M |
| EPS (TTM) | $-1.46 |
| Exchange | NCM |
đ Comprehensive Analysis
Company Data
| Enterprise Value | $41.12M |
| Sales | $38K |
| Income | $-51.55M |
| Book/sh | $0.18 |
| Cash/sh | $0.54 |
| Employees | 39 |
Financial Ratios
| Debt/Eq | 516.93 |
Returns & Margins
| Operating Margin | -71362.50% |
Ownership
| Insider Ownership | 47.91% |
| Institutional Ownership | 18.54% |
| Insider & Institutional transactions data not available | |
Valuation Ratios
| Forward P/E | -0.98 |
| P/S | 763.62 |
| P/B | 5.15 |
Analyst Data
| Recommendation | strong_buy |
| Target Price | $13.00 |
Technical Indicators
| SMA20 | $0.97 |
| SMA50 | $0.98 |
| SMA200 | $1.26 |
| RSI | 47.13 |
| ATR | 0.0597 |
| Shares Float | 14.43M |
| Short Float | 3.28% |
| Short Ratio | 2.73 |
| Volatility | 2.09 |
| Rel Volume | 0.66 |
Performance History
| Week | -5.38% |
| Month | +5.91% |
| Quarter | +3.44% |
| 6 Months | -25.44% |
| YTD | -15.27% |
| Year | -66.47% |
| 3 Years | -90.95% |
| 5 Years | -99.07% |
| 10 Years | -99.07% |
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Recent Price History
| Date | Close | Volume |
|---|---|---|
| 2026-06-18 | $0.93 | 114,900 |
| 2026-06-17 | $0.95 | 111,700 |
| 2026-06-16 | $0.93 | 121,900 |
| 2026-06-15 | $0.97 | 238,400 |
| 2026-06-12 | $0.96 | 76,400 |
| 2026-06-11 | $0.99 | 108,400 |
| 2026-06-10 | $0.96 | 206,500 |
| 2026-06-09 | $0.91 | 178,400 |
| 2026-06-08 | $0.94 | 106,900 |
| 2026-06-05 | $0.96 | 225,600 |
| 2026-06-04 | $1.00 | 133,600 |
| 2026-06-03 | $0.98 | 148,000 |
| 2026-06-02 | $0.98 | 263,500 |
| 2026-06-01 | $0.98 | 278,000 |
| 2026-05-29 | $0.95 | 171,500 |
| 2026-05-28 | $1.00 | 131,800 |
| 2026-05-27 | $1.01 | 229,400 |
| 2026-05-26 | $0.99 | 259,100 |
| 2026-05-22 | $0.99 | 155,800 |
| 2026-05-21 | $0.98 | 246,900 |
| 2026-05-20 | $0.98 | 178,800 |
| 2026-05-19 | $0.88 | 202,700 |
About Senti Biosciences Holdings, Inc.
Senti Biosciences Holdings, Inc., a clinical stage biotechnology company, develops cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The company's lead product candidates utilize off-the-shelf healthy adult donor derived natural killer (NK) cells to create CAR-NK cells outfitted with gene circuit technologies in various oncology indications with unmet need. It offers SENTI-202, a logic gated off-the-shelf CAR-NK cell therapy for the treatment of blood cancers and relapsed/refractory hematological malignancies, including acute myeloid leukemia. In addition, the company develops the tumor-associated antigen and protective antigen paired discovery platform to select and validate NOT GATE antigen candidates and identify tumor-associated antigens in cancer cells. Further, its pipeline includes preclinical programs, which comprise a solid tumor cell therapy program; and partnered programs related to cell therapies for regenerative medicines. The company has a strategic collaboration with Celest Therapeutics (Shanghai) Co. Ltd. The company was formerly known as Senti Biosciences, Inc. and changed its name to Senti Biosciences Holdings, Inc. in April 2026. The company was incorporated in 2016 and is headquartered in South San Francisco, California.
Income Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Revenue | ||||
| Total Revenue | $22,000 | $0 | $1,978,000 | $3,286,000 |
| Operating Revenue | $22,000 | $0 | $1,978,000 | $3,286,000 |
| Expenses | ||||
| Total Expenses | $63,749,000 | $60,726,000 | $68,743,000 | $65,370,000 |
| Other Income Expense | $1,362,000 | $6,988,000 | $-19,505,000 | $10,718,000 |
| Other Non Operating Income Expenses | $6,414,000 | $20,006,000 | $2,290,000 | $-32,000 |
| Net Non Operating Interest Income Expense | $927,000 | $948,000 | $2,864,000 | $1,701,000 |
| Operating Expense | $63,749,000 | $60,726,000 | $68,743,000 | $65,370,000 |
| General And Administrative Expense | $23,428,000 | $23,510,000 | $34,868,000 | $37,633,000 |
| Other Operating Expenses | - | - | $-583,000 | $-1,000,000 |
| Income & Earnings | ||||
| Net Income From Continuing Operation Net Minority Interest | $-61,438,000 | $-52,790,000 | $-83,406,000 | $-49,665,000 |
| Net Interest Income | $927,000 | $948,000 | $2,864,000 | $1,701,000 |
| Interest Income | $927,000 | $948,000 | $2,864,000 | $1,701,000 |
| Normalized Income | $-56,386,000 | $-39,772,000 | $-61,611,000 | $-60,415,000 |
| Net Income From Continuing And Discontinued Operation | $-61,438,000 | $-52,790,000 | $-71,058,000 | $-58,210,000 |
| Total Operating Income As Reported | $-68,779,000 | $-61,039,000 | $-92,727,000 | $-62,084,000 |
| Net Income Common Stockholders | $-61,438,000 | $-52,790,000 | $-71,058,000 | $-58,210,000 |
| Net Income | $-61,438,000 | $-52,790,000 | $-71,058,000 | $-58,210,000 |
| Net Income Including Noncontrolling Interests | $-61,438,000 | $-52,790,000 | $-71,058,000 | $-58,210,000 |
| Net Income Continuous Operations | $-61,438,000 | $-52,790,000 | $-83,406,000 | $-49,665,000 |
| Pretax Income | $-61,438,000 | $-52,790,000 | $-83,406,000 | $-49,665,000 |
| Special Income Charges | $-5,052,000 | $-293,000 | $-25,755,000 | $10,750,000 |
| Interest Income Non Operating | $927,000 | $948,000 | $2,864,000 | $1,701,000 |
| Operating Income | $-63,727,000 | $-60,726,000 | $-66,765,000 | $-62,084,000 |
| Depreciation Amortization Depletion Income Statement | $2,735,000 | $2,860,000 | $2,308,000 | $592,000 |
| Depreciation And Amortization In Income Statement | $2,735,000 | $2,860,000 | $2,308,000 | $592,000 |
| Net Income Discontinuous Operations | - | $0 | $12,348,000 | $-8,545,000 |
| Per Share | ||||
| Diluted EPS | $-2.73 | $-12.03 | $-16.01 | $-22.30 |
| Basic EPS | $-2.73 | $-12.03 | $-16.01 | $-22.30 |
| Other | ||||
| Tax Effect Of Unusual Items | $0 | $0 | $0 | $0 |
| Tax Rate For Calcs | $0 | $0 | $0 | $0 |
| Normalized EBITDA (Bullshit earnings) | $-55,038,000 | $-43,870,000 | $-39,541,000 | $-68,914,000 |
| Total Unusual Items | $-5,052,000 | $-13,018,000 | $-21,795,000 | $10,750,000 |
| Total Unusual Items Excluding Goodwill | $-5,052,000 | $-13,018,000 | $-21,795,000 | $10,750,000 |
| Reconciled Depreciation | $3,637,000 | $3,838,000 | $5,429,000 | $3,920,000 |
| EBITDA (Bullshit earnings) | $-60,090,000 | $-56,888,000 | $-61,336,000 | $-58,164,000 |
| EBIT | $-63,727,000 | $-60,726,000 | $-66,765,000 | $-62,084,000 |
| Diluted Average Shares | $22,483,391 | $4,595,946 | $4,437,106 | $2,611,078 |
| Basic Average Shares | $22,483,391 | $4,595,946 | $4,437,106 | $2,611,078 |
| Diluted NI Availto Com Stockholders | $-61,438,000 | $-52,790,000 | $-71,058,000 | $-58,210,000 |
| Impairment Of Capital Assets | $5,052,000 | $313,000 | $25,962,000 | $0 |
| Restructuring And Mergern Acquisition | $0 | $-20,000 | $-207,000 | $-9,461,000 |
| Research And Development | $37,586,000 | $34,356,000 | $32,150,000 | $28,145,000 |
| Selling General And Administration | $23,428,000 | $23,510,000 | $34,868,000 | $37,633,000 |
| Other Gand A | $11,915,000 | $15,131,000 | $11,751,000 | $8,914,000 |
| Salaries And Wages | $11,513,000 | $8,379,000 | $23,117,000 | $27,512,000 |
| Gain On Sale Of Security | - | $-12,725,000 | $3,960,000 | - |
| Insurance And Claims | - | - | $1,658,000 | $1,207,000 |
| Other Special Charges | - | - | - | $-1,289,000 |
Balance Sheet (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Assets | ||||
| Net Tangible Assets | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Total Assets | $51,223,000 | $97,841,000 | $119,484,000 | $180,792,000 |
| Total Non Current Assets | $27,949,000 | $38,880,000 | $48,284,000 | $78,213,000 |
| Other Non Current Assets | $3,547,000 | $3,643,000 | $3,737,000 | $8,434,000 |
| Current Assets | $23,274,000 | $58,961,000 | $71,200,000 | $102,579,000 |
| Prepaid Assets | $5,259,000 | $8,295,000 | $17,375,000 | $3,080,000 |
| Receivables | $1,595,000 | $1,805,000 | $17,704,000 | $626,000 |
| Accounts Receivable | $323,000 | $159,000 | $112,000 | $626,000 |
| Cash Cash Equivalents And Short Term Investments | $16,420,000 | $48,277,000 | $35,926,000 | $98,563,000 |
| Cash And Cash Equivalents | $16,420,000 | $48,277,000 | $35,926,000 | $57,621,000 |
| Other Current Assets | - | $584,000 | $195,000 | $101,000 |
| Cash Equivalents | - | $35,869,000 | $31,721,000 | - |
| Cash Financial | - | $12,408,000 | $4,205,000 | - |
| Non Current Accounts Receivable | - | - | $2,935,000 | - |
| Assets Held For Sale Current | - | - | $0 | $209,000 |
| Current Deferred Assets | - | - | - | $0 |
| Debt | ||||
| Total Debt | $28,891,000 | $33,538,000 | $37,666,000 | $37,091,000 |
| Long Term Debt And Capital Lease Obligation | $23,561,000 | $28,891,000 | $33,538,000 | $35,103,000 |
| Current Debt And Capital Lease Obligation | $5,330,000 | $4,647,000 | $4,128,000 | $1,988,000 |
| Liabilities | ||||
| Total Liabilities Net Minority Interest | $45,634,000 | $72,192,000 | $52,571,000 | $53,529,000 |
| Total Non Current Liabilities Net Minority Interest | $31,660,000 | $59,046,000 | $39,899,000 | $35,476,000 |
| Other Non Current Liabilities | $149,000 | $149,000 | $20,000 | $227,000 |
| Non Current Deferred Liabilities | $7,950,000 | $4,900,000 | - | $0 |
| Current Liabilities | $13,974,000 | $13,146,000 | $12,672,000 | $18,053,000 |
| Other Current Liabilities | $73,000 | $433,000 | $378,000 | $1,320,000 |
| Current Deferred Liabilities | $347,000 | $660,000 | $989,000 | $799,000 |
| Payables And Accrued Expenses | $5,859,000 | $4,864,000 | $4,814,000 | $12,237,000 |
| Payables | $2,943,000 | $1,454,000 | $1,250,000 | $1,370,000 |
| Accounts Payable | $2,943,000 | $1,454,000 | $1,250,000 | $1,370,000 |
| Derivative Product Liabilities | - | $0 | $6,341,000 | $146,000 |
| Equity | ||||
| Common Stock Equity | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Total Equity Gross Minority Interest | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Stockholders Equity | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Retained Earnings | $-358,572,000 | $-297,134,000 | $-244,344,000 | $-173,286,000 |
| Preferred Securities Outside Stock Equity | $0 | $25,106,000 | $0 | $0 |
| Gains Losses Not Affecting Retained Earnings | - | - | $0 | $1,000 |
| Other Equity Adjustments | - | - | - | $1,000 |
| Other | ||||
| Ordinary Shares Number | $30,879,355 | $4,829,035 | $4,570,016 | $4,406,253 |
| Share Issued | $30,879,355 | $4,829,035 | $4,570,016 | $4,406,253 |
| Tangible Book Value | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Invested Capital | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Working Capital | $9,300,000 | $45,815,000 | $58,528,000 | $84,526,000 |
| Capital Lease Obligations | $28,891,000 | $33,538,000 | $37,666,000 | $37,091,000 |
| Total Capitalization | $5,589,000 | $25,649,000 | $66,913,000 | $127,263,000 |
| Additional Paid In Capital | $364,158,000 | $322,782,000 | $311,256,000 | $300,544,000 |
| Capital Stock | $3,000 | $1,000 | $1,000 | $4,000 |
| Common Stock | $3,000 | $1,000 | $1,000 | $4,000 |
| Non Current Deferred Revenue | $7,950,000 | $4,900,000 | - | $0 |
| Long Term Capital Lease Obligation | $23,561,000 | $28,891,000 | $33,538,000 | $35,103,000 |
| Current Deferred Revenue | $347,000 | $660,000 | $989,000 | $799,000 |
| Current Capital Lease Obligation | $5,330,000 | $4,647,000 | $4,128,000 | $1,988,000 |
| Pensionand Other Post Retirement Benefit Plans Current | $2,365,000 | $2,542,000 | $2,363,000 | $1,709,000 |
| Current Accrued Expenses | $2,916,000 | $3,410,000 | $3,564,000 | $10,867,000 |
| Net PPE | $24,402,000 | $35,237,000 | $41,612,000 | $69,779,000 |
| Accumulated Depreciation | $-13,057,000 | $-9,551,000 | $-6,182,000 | $-2,955,000 |
| Gross PPE | $37,459,000 | $44,788,000 | $47,794,000 | $72,734,000 |
| Leases | $17,748,000 | $22,660,000 | $22,648,000 | $1,869,000 |
| Other Properties | $19,081,000 | $21,498,000 | $24,460,000 | $26,273,000 |
| Machinery Furniture Equipment | $630,000 | $630,000 | $686,000 | $700,000 |
| Properties | $0 | $0 | $0 | $0 |
| Duefrom Related Parties Current | $1,272,000 | $1,646,000 | $17,592,000 | $0 |
| Duefrom Related Parties Non Current | - | $0 | $2,935,000 | $0 |
| Construction In Progress | - | - | $0 | $43,892,000 |
| Other Short Term Investments | - | - | $0 | $40,942,000 |
| Preferred Stock | - | - | - | $0 |
Cash Flow Statement (Annual)
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 |
|---|---|---|---|---|
| Free Cash Flow | ||||
| Free Cash Flow | $-43,640,000 | $-41,423,000 | $-64,433,000 | $-76,270,000 |
| Operating Activities | ||||
| Operating Cash Flow | $-43,444,000 | $-41,397,000 | $-52,395,000 | $-34,896,000 |
| Cash Flow From Continuing Operating Activities | $-43,444,000 | $-41,397,000 | $-52,395,000 | $-34,896,000 |
| Operating Gains Losses | - | $-6,331,000 | $-25,180,000 | $-1,289,000 |
| Investing Activities | ||||
| Capital Expenditure | $-196,000 | $-26,000 | $-12,038,000 | $-41,374,000 |
| Investing Cash Flow | $-184,000 | $34,000 | $30,077,000 | $-81,959,000 |
| Cash Flow From Continuing Investing Activities | $-184,000 | $34,000 | $30,077,000 | $-81,959,000 |
| Financing Activities | ||||
| Issuance Of Capital Stock | $0 | $49,059,000 | $512,000 | $728,000 |
| Financing Cash Flow | $11,761,000 | $53,730,000 | $779,000 | $118,551,000 |
| Cash Flow From Continuing Financing Activities | $11,761,000 | $53,730,000 | $779,000 | $118,551,000 |
| Net Other Financing Charges | $581,000 | $4,671,000 | - | $111,976,000 |
| Net Common Stock Issuance | $0 | $49,059,000 | $512,000 | $728,000 |
| Common Stock Issuance | $0 | $49,059,000 | $512,000 | $728,000 |
| Net Preferred Stock Issuance | - | - | - | $0 |
| Preferred Stock Issuance | - | - | - | $0 |
| Other | ||||
| End Cash Position | $19,948,000 | $51,815,000 | $39,448,000 | $60,987,000 |
| Beginning Cash Position | $51,815,000 | $39,448,000 | $60,987,000 | $59,291,000 |
| Changes In Cash | $-31,867,000 | $12,367,000 | $-21,539,000 | $1,696,000 |
| Proceeds From Stock Option Exercised | $11,180,000 | $0 | $375,000 | $672,000 |
| Net PPE Purchase And Sale | $-184,000 | $34,000 | $-11,933,000 | $-41,374,000 |
| Sale Of PPE | $12,000 | $60,000 | $105,000 | $0 |
| Purchase Of PPE | $-196,000 | $-26,000 | $-12,038,000 | $-41,374,000 |
| Change In Working Capital | $3,560,000 | $6,071,000 | $4,665,000 | $13,904,000 |
| Change In Other Working Capital | $-313,000 | $-329,000 | $-110,000 | $-1,033,000 |
| Change In Other Current Liabilities | $-4,647,000 | $-3,882,000 | $484,000 | $14,129,000 |
| Change In Other Current Assets | $2,292,000 | $2,013,000 | - | - |
| Change In Payables And Accrued Expense | $2,302,000 | $126,000 | $426,000 | $2,241,000 |
| Change In Accrued Expense | $559,000 | $-671,000 | $716,000 | $2,055,000 |
| Change In Payable | $1,743,000 | $797,000 | $-290,000 | $186,000 |
| Change In Account Payable | $1,743,000 | $797,000 | $-290,000 | $186,000 |
| Change In Prepaid Assets | $3,716,000 | $8,855,000 | $4,794,000 | $-1,302,000 |
| Change In Receivables | $210,000 | $-712,000 | $-929,000 | $-131,000 |
| Changes In Account Receivables | $-164,000 | $-47,000 | $507,000 | $-131,000 |
| Other Non Cash Items | $39,000 | $5,747,000 | $-814,000 | $-9,613,000 |
| Stock Based Compensation | $5,706,000 | $1,755,000 | $9,670,000 | $16,392,000 |
| Asset Impairment Charge | $5,052,000 | $313,000 | $25,962,000 | $12,000 |
| Depreciation Amortization Depletion | $3,637,000 | $3,838,000 | $5,429,000 | $3,920,000 |
| Depreciation And Amortization | $3,637,000 | $3,838,000 | $5,429,000 | $3,920,000 |
| Depreciation | $3,637,000 | $3,838,000 | $5,429,000 | $3,920,000 |
| Net Income From Continuing Operations | $-61,438,000 | $-52,790,000 | $-71,058,000 | $-58,222,000 |
| Repayment Of Debt | - | $0 | $-108,000 | $0 |
| Net Issuance Payments Of Debt | - | $0 | $-108,000 | $5,175,000 |
| Net Long Term Debt Issuance | - | $0 | $-108,000 | $5,175,000 |
| Long Term Debt Payments | - | $0 | $-108,000 | $0 |
| Net Investment Purchase And Sale | - | $0 | $42,010,000 | $-40,585,000 |
| Sale Of Investment | - | $0 | $60,000,000 | $0 |
| Purchase Of Investment | - | $0 | $-17,990,000 | $-40,585,000 |
| Amortization Of Securities | - | $0 | $-1,069,000 | $-356,000 |
| Gain Loss On Investment Securities | - | $-6,331,000 | $-3,318,000 | - |
| Gain Loss On Sale Of Business | - | $0 | $-21,862,000 | $0 |
| Issuance Of Debt | - | - | $0 | $5,175,000 |
| Long Term Debt Issuance | - | - | $0 | $5,175,000 |