S&P 500 7,387.05 â–ŧ 197.26 (-2.60%) DOW 50,877.30 â–ŧ 684.63 (-1.33%) NASDAQ 25,726.49 â–ŧ 1,104.47 (-4.12%) US Markets Closed â€ĸ 05:42 PM ET

VRTX

Vertex Pharmaceuticals Incorporated

Price Chart
Latest Quote

$446.83

+5.09 (+1.15%)
Current Price
Previous Close $441.74
Open $446.03
Day High $453.16
Day Low $443.86
Volume 1,528,438
Fetched: 2026-06-05T21:42:33
Stock Information
Shares Outstanding 253.81M
Total Debt $1.99B
Cash Equivalents $7.25B
Revenue $12.22B
Net Income $4.34B
Sector Healthcare
Industry Biotechnology
Market Cap $113.41B
P/E Ratio 26.55
EPS (TTM) $16.83
Exchange NMS
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📊 Comprehensive Analysis
Company Data
Enterprise Value$106.86B
Sales$12.22B
Income$4.34B
Book/sh$76.18
Cash/sh$28.55
Employees6K
Financial Ratios
Quick Ratio2.38
Current Ratio3.02
Debt/Eq10.26
EPS Growth TTM59.60%
Returns & Margins
ROA12.14%
ROE24.20%
Gross Margin54.39%
Operating Margin38.13%
Profit Margin35.51%
Ownership
Insider Ownership0.20%
Institutional Ownership97.89%
Insider & Institutional transactions data not available
Valuation Ratios
Forward P/E20.81
PEG1.60
P/S9.28
P/B5.87
Analyst Data
Recommendationbuy
Target Price$548.69
Technical Indicators
SMA20$438.61
SMA50$436.94
SMA200$437.17
RSI57.19
ATR11.2214
Shares Float253.02M
Short Float1.99%
Short Ratio3.97
Volatility0.31
Rel Volume1.14
Performance History
Week-0.16%
Month+4.48%
Quarter-2.16%
6 Months-3.52%
YTD-1.17%
Year+0.22%
3 Years+38.09%
5 Years+114.17%
10 Years+365.01%
Stock Score: ⭐ Premium
Based on debt, profitability, growth, and cash flow metrics
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Recent Price History
Date Close Volume
2026-06-05 $446.83 1,528,438
2026-06-04 $441.74 1,362,300
2026-06-03 $428.34 1,564,400
2026-06-02 $425.09 1,147,100
2026-06-01 $438.40 1,115,200
2026-05-29 $447.54 1,893,400
2026-05-28 $447.97 1,357,900
2026-05-27 $437.22 1,164,400
2026-05-26 $435.93 865,800
2026-05-22 $434.52 1,746,300
2026-05-21 $433.54 1,395,200
2026-05-20 $430.44 1,784,800
2026-05-19 $434.31 1,219,500
2026-05-18 $436.58 1,451,000
2026-05-15 $436.95 1,288,900
2026-05-14 $450.41 1,088,200
2026-05-13 $453.06 1,194,200
2026-05-12 $448.29 1,398,000
2026-05-11 $435.17 1,264,200
2026-05-08 $429.82 953,300
2026-05-07 $425.00 1,112,300
2026-05-06 $427.65 1,203,200
About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of SCD and TDT; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease, which is in single Phase 2 trial; VX-264 for treating Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. The company sells its products primarily to specialty pharmacy and distributors, wholesalers, retail pharmacies, hospitals, and clinics. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Period:
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Income Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Revenue
Reconciled Cost Of Revenue $1,651,300,000 $1,530,500,000 $1,262,200,000 $1,080,300,000
Cost Of Revenue $1,651,300,000 $1,530,500,000 $1,262,200,000 $1,080,300,000
Total Revenue $12,001,300,000 $11,020,100,000 $9,869,200,000 $8,930,700,000
Operating Revenue $11,970,600,000 $11,020,100,000 $9,869,200,000 $8,930,700,000
Expenses
Interest Expense $13,300,000 $30,600,000 $44,100,000 $54,800,000
Total Expenses $7,446,900,000 $11,253,500,000 $6,088,800,000 $4,680,800,000
Other Income Expense $-388,800,000 $-85,600,000 $28,800,000 $-107,300,000
Other Non Operating Income Expenses $-7,700,000 $-86,100,000 $-22,800,000 $-164,800,000
Net Non Operating Interest Income Expense $477,600,000 $567,500,000 $570,600,000 $89,800,000
Interest Expense Non Operating $13,300,000 $30,600,000 $44,100,000 $54,800,000
Operating Expense $5,795,600,000 $9,723,000,000 $4,826,600,000 $3,600,500,000
Income & Earnings
Net Income From Continuing Operation Net Minority Interest $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Interest Income $477,600,000 $567,500,000 $570,600,000 $89,800,000
Interest Income $490,900,000 $598,100,000 $614,700,000 $144,600,000
Normalized Income $4,277,666,859 $-535,995,000 $3,576,978,400 $3,276,862,500
Net Income From Continuing And Discontinued Operation $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Total Operating Income As Reported $4,173,300,000 $-232,900,000 $3,832,000,000 $4,307,400,000
Net Income Common Stockholders $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Income $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Income Including Noncontrolling Interests $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Income Continuous Operations $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Pretax Income $4,643,200,000 $248,500,000 $4,379,800,000 $4,232,400,000
Special Income Charges $-381,100,000 $500,000 $51,600,000 $57,500,000
Interest Income Non Operating $490,900,000 $598,100,000 $614,700,000 $144,600,000
Operating Income $4,554,400,000 $-233,400,000 $3,780,400,000 $4,249,900,000
Gross Profit $10,350,000,000 $9,489,600,000 $8,607,000,000 $7,850,400,000
Per Share
Diluted EPS $15.32 $-2.08 $13.89 $12.82
Basic EPS $15.46 $-2.08 $14.05 $12.97
Other
Tax Effect Of Unusual Items $-56,633,141 $105,000 $8,978,400 $12,362,500
Tax Rate For Calcs $0 $0 $0 $0
Normalized EBITDA (Bullshit earnings) $5,247,400,000 $485,800,000 $4,553,600,000 $4,378,000,000
Total Unusual Items $-381,100,000 $500,000 $51,600,000 $57,500,000
Total Unusual Items Excluding Goodwill $-381,100,000 $500,000 $51,600,000 $57,500,000
Reconciled Depreciation $209,800,000 $207,200,000 $181,300,000 $148,300,000
EBITDA (Bullshit earnings) $4,866,300,000 $486,300,000 $4,605,200,000 $4,435,500,000
EBIT $4,656,500,000 $279,100,000 $4,423,900,000 $4,287,200,000
Diluted Average Shares $258,000,000 $257,900,000 $260,500,000 $259,100,000
Basic Average Shares $255,700,000 $257,900,000 $257,700,000 $256,100,000
Diluted NI Availto Com Stockholders $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Tax Provision $690,000,000 $784,100,000 $760,200,000 $910,400,000
Impairment Of Capital Assets $379,000,000 $0 $0 -
Restructuring And Mergern Acquisition $2,100,000 $-500,000 $-51,600,000 $-57,500,000
Research And Development $4,042,500,000 $8,258,700,000 $3,690,000,000 $2,655,800,000
Selling General And Administration $1,753,100,000 $1,464,300,000 $1,136,600,000 $944,700,000
Other Special Charges - $4,628,400,000 $527,100,000 $115,500,000
Fetched: 2026-05-26
Balance Sheet (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Assets
Net Tangible Assets $17,153,600,000 $14,495,700,000 $15,652,500,000 $12,221,100,000
Total Assets $25,643,000,000 $22,533,200,000 $22,730,200,000 $18,150,900,000
Total Non Current Assets $14,442,000,000 $12,936,800,000 $8,586,000,000 $4,916,100,000
Other Non Current Assets $1,236,600,000 $999,300,000 $895,300,000 $409,600,000
Non Current Deferred Assets $2,897,900,000 $2,331,100,000 $1,812,100,000 $1,246,900,000
Non Current Deferred Taxes Assets $2,897,900,000 $2,331,100,000 $1,812,100,000 $1,246,900,000
Investmentin Financial Assets $5,712,300,000 $5,107,900,000 $2,497,800,000 $112,200,000
Goodwill And Other Intangible Assets $1,512,200,000 $1,913,900,000 $1,927,900,000 $1,691,600,000
Other Intangible Assets $424,200,000 $825,900,000 $839,900,000 $603,600,000
Current Assets $11,201,000,000 $9,596,400,000 $14,144,200,000 $13,234,800,000
Other Current Assets $110,900,000 $76,400,000 $84,300,000 $74,400,000
Hedging Assets Current $6,200,000 $130,100,000 $1,800,000 $47,500,000
Prepaid Assets $736,200,000 $459,200,000 $537,600,000 $431,600,000
Inventory $1,686,800,000 $1,205,400,000 $738,800,000 $460,600,000
Receivables $2,052,800,000 $1,609,400,000 $1,563,400,000 $1,442,200,000
Accounts Receivable $2,052,800,000 $1,609,400,000 $1,563,400,000 $1,442,200,000
Cash Cash Equivalents And Short Term Investments $6,608,100,000 $6,115,900,000 $11,218,300,000 $10,778,500,000
Cash And Cash Equivalents $5,084,800,000 $4,569,600,000 $10,369,100,000 $10,504,000,000
Debt
Total Debt $2,030,500,000 $1,744,300,000 $808,400,000 $899,700,000
Long Term Debt And Capital Lease Obligation $1,953,200,000 $1,657,200,000 $724,700,000 $810,300,000
Current Debt And Capital Lease Obligation $77,300,000 $87,100,000 $83,700,000 $89,400,000
Liabilities
Total Liabilities Net Minority Interest $6,977,200,000 $6,123,600,000 $5,149,800,000 $4,238,200,000
Total Non Current Liabilities Net Minority Interest $3,116,000,000 $2,559,000,000 $1,602,400,000 $1,496,100,000
Other Non Current Liabilities $267,400,000 $203,200,000 $196,300,000 $233,000,000
Tradeand Other Payables Non Current $895,400,000 $698,600,000 $681,400,000 $452,800,000
Current Liabilities $3,861,200,000 $3,564,600,000 $3,547,400,000 $2,742,100,000
Other Current Liabilities $127,700,000 $36,600,000 $50,700,000 $62,500,000
Current Deferred Liabilities $171,800,000 $206,800,000 $170,300,000 $159,600,000
Payables And Accrued Expenses $3,484,400,000 $3,234,100,000 $3,242,700,000 $2,430,600,000
Payables $893,000,000 $877,600,000 $924,500,000 $642,200,000
Other Payable $328,200,000 $303,500,000 $460,100,000 $215,000,000
Total Tax Payable $103,100,000 $161,100,000 $99,500,000 $123,300,000
Accounts Payable $461,700,000 $413,000,000 $364,900,000 $303,900,000
Equity
Common Stock Equity $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Total Equity Gross Minority Interest $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Stockholders Equity $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Gains Losses Not Affecting Retained Earnings $-15,900,000 $127,800,000 $-14,300,000 $800,000
Other Equity Adjustments $-15,900,000 $127,800,000 $-14,300,000 $800,000
Retained Earnings $13,560,000,000 $9,606,800,000 $10,142,400,000 $6,522,800,000
Other
Ordinary Shares Number $253,991,224 $256,940,382 $257,695,221 $257,011,628
Share Issued $253,991,224 $256,940,382 $257,695,221 $257,011,628
Tangible Book Value $17,153,600,000 $14,495,700,000 $15,652,500,000 $12,221,100,000
Invested Capital $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Working Capital $7,339,800,000 $6,031,800,000 $10,596,800,000 $10,492,700,000
Capital Lease Obligations $2,030,500,000 $1,744,300,000 $808,400,000 $899,700,000
Total Capitalization $18,665,800,000 $16,409,600,000 $17,580,400,000 $13,912,700,000
Additional Paid In Capital $5,119,200,000 $6,672,400,000 $7,449,700,000 $7,386,500,000
Capital Stock $2,500,000 $2,600,000 $2,600,000 $2,600,000
Common Stock $2,500,000 $2,600,000 $2,600,000 $2,600,000
Preferred Stock $0 $0 $0 $0
Long Term Capital Lease Obligation $1,953,200,000 $1,657,200,000 $724,700,000 $810,300,000
Current Deferred Revenue $171,800,000 $206,800,000 $170,300,000 $159,600,000
Current Capital Lease Obligation $77,300,000 $87,100,000 $83,700,000 $89,400,000
Current Accrued Expenses $2,591,400,000 $2,356,500,000 $2,318,200,000 $1,788,400,000
Investments And Advances $5,712,300,000 $5,107,900,000 $2,497,800,000 $112,200,000
Available For Sale Securities $5,712,300,000 $5,107,900,000 $2,497,800,000 $112,200,000
Goodwill $1,088,000,000 $1,088,000,000 $1,088,000,000 $1,088,000,000
Net PPE $3,083,000,000 $2,584,600,000 $1,452,900,000 $1,455,800,000
Accumulated Depreciation $-1,204,100,000 $-1,064,800,000 $-1,188,900,000 $-1,027,300,000
Gross PPE $4,287,100,000 $3,649,400,000 $2,641,800,000 $2,483,100,000
Leases $1,009,300,000 $737,600,000 $474,600,000 $410,900,000
Other Properties $1,562,700,000 $1,356,800,000 $293,600,000 $347,400,000
Machinery Furniture Equipment $1,198,200,000 $1,060,700,000 $911,900,000 $788,600,000
Buildings And Improvements $483,800,000 $461,200,000 $928,600,000 $903,100,000
Land And Improvements $33,100,000 $33,100,000 $33,100,000 $33,100,000
Properties $0 $0 $0 $0
Finished Goods $230,100,000 $184,600,000 $135,000,000 $161,800,000
Work In Process $1,196,900,000 $768,800,000 $525,100,000 $260,700,000
Raw Materials $259,800,000 $252,000,000 $78,700,000 $38,100,000
Other Short Term Investments $1,523,300,000 $1,546,300,000 $849,200,000 $274,500,000
Treasury Shares Number - - $0 $0
Fetched: 2026-05-26
Cash Flow Statement (Annual)
Metric 2025-12-31 2024-12-31 2023-12-31 2022-12-31
Free Cash Flow
Free Cash Flow $3,193,800,000 $-978,000,000 $3,278,900,000 $3,925,200,000
Operating Activities
Operating Cash Flow $3,631,400,000 $-492,600,000 $3,537,300,000 $4,129,900,000
Cash Flow From Continuing Operating Activities $3,631,400,000 $-492,600,000 $3,537,300,000 $4,129,900,000
Operating Gains Losses - $57,700,000 $600,000 $149,100,000
Investing Activities
Capital Expenditure $-437,600,000 $-485,400,000 $-258,400,000 $-204,700,000
Investing Cash Flow $-945,400,000 $-3,770,000,000 $-3,141,700,000 $-321,100,000
Cash Flow From Continuing Investing Activities $-945,400,000 $-3,770,000,000 $-3,141,700,000 $-321,100,000
Net Other Investing Changes $-24,700,000 $-54,000,000 $-31,000,000 $-47,800,000
Financing Activities
Repurchase Of Capital Stock $-2,387,300,000 $-1,582,100,000 $-653,700,000 $-172,000,000
Financing Cash Flow $-2,261,300,000 $-1,494,900,000 $-562,200,000 $-67,700,000
Cash Flow From Continuing Financing Activities $-2,261,300,000 $-1,494,900,000 $-562,200,000 $-67,700,000
Net Other Financing Charges $3,700,000 $6,200,000 $1,800,000 $3,500,000
Net Common Stock Issuance $-2,387,300,000 $-1,582,100,000 $-653,700,000 $-172,000,000
Other
Repayment Of Debt $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Interest Paid Supplemental Data $12,400,000 $30,500,000 $43,100,000 $52,300,000
Income Tax Paid Supplemental Data $1,566,700,000 $1,082,100,000 $1,677,300,000 $1,057,800,000
End Cash Position $5,087,800,000 $4,572,200,000 $10,372,300,000 $10,512,000,000
Beginning Cash Position $4,572,200,000 $10,372,300,000 $10,512,000,000 $6,800,100,000
Effect Of Exchange Rate Changes $90,900,000 $-42,600,000 $26,900,000 $-29,200,000
Changes In Cash $424,700,000 $-5,757,500,000 $-166,600,000 $3,741,100,000
Proceeds From Stock Option Exercised $127,700,000 $114,600,000 $134,600,000 $186,300,000
Common Stock Payments $-2,387,300,000 $-1,582,100,000 $-653,700,000 $-172,000,000
Net Issuance Payments Of Debt $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Net Long Term Debt Issuance $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Long Term Debt Payments $-5,400,000 $-33,600,000 $-44,900,000 $-85,500,000
Net Investment Purchase And Sale $-483,100,000 $-3,230,600,000 $-2,852,300,000 $227,300,000
Sale Of Investment $5,913,400,000 $4,465,600,000 $934,200,000 $920,000,000
Purchase Of Investment $-6,396,500,000 $-7,696,200,000 $-3,786,500,000 $-692,700,000
Net Intangibles Purchase And Sale $0 $-187,700,000 $-58,000,000 $0
Purchase Of Intangibles $0 $-187,700,000 $-58,000,000 $0
Net PPE Purchase And Sale $-437,600,000 $-297,700,000 $-200,400,000 $-204,700,000
Purchase Of PPE $-437,600,000 $-297,700,000 $-200,400,000 $-204,700,000
Change In Working Capital $-1,199,100,000 $-514,800,000 $-265,700,000 $340,800,000
Change In Other Current Liabilities $148,500,000 $39,700,000 $208,900,000 $498,900,000
Change In Payables And Accrued Expense $-80,100,000 $262,400,000 $478,100,000 $663,300,000
Change In Accrued Expense $-116,900,000 $212,900,000 $429,400,000 $542,500,000
Change In Payable $36,800,000 $49,500,000 $48,700,000 $120,800,000
Change In Account Payable $36,800,000 $49,500,000 $48,700,000 $120,800,000
Change In Prepaid Assets $-396,000,000 $-200,300,000 $-545,700,000 $-326,400,000
Change In Inventory $-524,200,000 $-517,300,000 $-322,900,000 $-136,400,000
Change In Receivables $-347,300,000 $-99,300,000 $-84,100,000 $-358,600,000
Changes In Account Receivables $-347,300,000 $-99,300,000 $-84,100,000 $-358,600,000
Other Non Cash Items $113,400,000 $900,000 $-42,600,000 $-45,700,000
Stock Based Compensation $685,900,000 $698,500,000 $581,200,000 $491,300,000
Asset Impairment Charge $379,000,000 $0 $0 -
Deferred Tax $-510,800,000 $-348,800,000 $-536,500,000 $-275,900,000
Deferred Income Tax $-510,800,000 $-348,800,000 $-536,500,000 $-275,900,000
Depreciation Amortization Depletion $209,800,000 $207,200,000 $181,300,000 $148,300,000
Depreciation And Amortization $209,800,000 $207,200,000 $181,300,000 $148,300,000
Net Income From Continuing Operations $3,953,200,000 $-535,600,000 $3,619,600,000 $3,322,000,000
Net Business Purchase And Sale - $0 $0 $-295,900,000
Purchase Of Business - $0 $0 $-295,900,000
Gain Loss On Investment Securities - $57,700,000 $600,000 $149,100,000
Issuance Of Debt - - $1,800,000 $0
Long Term Debt Issuance - - $1,800,000 $0
Depreciation - - - $148,300,000
Fetched: 2026-05-26